University of Oulu

Ratcliffe P, Koivunen P, Myllyharju J, Ragoussis J, Bovée JV, Batinic-Haberle I, Vinatier C, Trichet V, Robriquet F, Oliver L, Gardie B. Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways : from physiology to therapeutics. Hypoxia 2017:5 11–20. DOI: 10.2147/HP.S127042

Update on hypoxia-inducible factors and hydroxylases in oxygen regulatory pathways : from physiology to therapeutics

Saved in:
Author: Ratcliffe, Peter1,2; Koivunen, Peppi3; Myllyharju, Johanna3;
Organizations: 1Target Discovery Institute, University of Oxford
2The Francis Crick Institute, London, UK
3Oulu Center for Cell-Matrix Research, Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu, Oulu, Finland
4McGill University and Genome Quebec Innovation Centre, McGill University, Montreal, Canada
5Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands
6Department of Radiation Oncology, Duke University School of Medicine, Durham, NC, USA
7INSERM UMR 1229, Regenerative Medicine and Skeleton-RMeS, Team STEP, University of Nantes, UFR Odontology
8UMR 1238 INSERM, Université de Nantes, Faculté de Médecine
9CRCINA, INSERM, Université de Nantes, Nantes
10Ecole Pratique des Hautes Etudes, PSL Research University, Paris, France
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.9 MB)
Persistent link:
Language: English
Published: Dove Medical Press, 2017
Publish Date: 2017-06-25


The “Hypoxia Nantes 2016” organized its second conference dedicated to the field of hypoxia research. This conference focused on “the role of hypoxia under physiological conditions as well as in cancer” and took place in Nantes, France, in October 6–7, 2016. The main objective of this conference was to bring together a large group of scientists from different spheres of hypoxia. Recent advances were presented and discussed around different topics: genomics, physiology, musculoskeletal, stem cells, microenvironment and cancer, and oxidative stress. This review summarizes the major highlights of the meeting.

see all

Series: Hypoxia
ISSN: 2324-1128
ISSN-E: 2324-1128
ISSN-L: 2324-1128
Volume: 5
Pages: 11 - 20
DOI: 10.2147/HP.S127042
Type of Publication: A2 Review article in a scientific journal
Field of Science: 3111 Biomedicine
Funding: The meeting “Hypoxia Nantes 2106” (https://hypoxia. was financially supported by Alliance Bio Expertise, Baker Ruskinn, the Région Pays de la Loire, project “ERRATA” and “EryCan”; Laboratory of Excellence GR-Ex, reference ANR-11-LABX-0051; Nantes University; and Dove Press.
Copyright information: © 2017 Ratcliffe et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (