University of Oulu

S. Aikio, M. Zeilinger, J. Hiltunen, L. Hakalahti, J. Hiitola-Keinänen, M. Hiltunen, V. Kontturi, S. Siitonen, J. Puustinen, P. Lieberzeit and P. Karioja, RSC Adv., 2016, 6, 50414 DOI: 10.1039/C6RA07320D

Disposable (bio)chemical integrated optical waveguide sensors implemented on roll-to-roll produced platforms

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Author: Aikio, Sanna1; Zeilinger, Martin2; Hiltunen, Jussi1;
Organizations: 1VTT Technical Research Centre of Finland, Kaitoväylä 1, Oulu, Finland
2University of Vienna, Faculty for Chemistry, Department of Analytical Chemistry, Währinger Straße 38, 1010 Vienna, Austria
3Nanocomp Oy Ltd, Ensolantie 6, FI-80710 Lehmo, Finland
4University of Oulu, Faculty of Information Technology and Electrical Engineering, Department of Electrical Engineering, Microelectronics and Materials Physics Laboratories, Pentti Kaiteran katu 1, FI-90014 Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.1 MB)
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Language: English
Published: Royal Society of Chemistry, 2016
Publish Date: 2017-07-03


To enable wide spread dissemination of sensors in cost-critical applications and resource poor settings, methods to implement sensor chips using low-cost materials and mass-manufacturing methods are developed. In this paper we demonstrate that disposable polymeric integrated Young interferometer (YI) sensor chips, implemented on roll-to-roll mass-manufactured waveguides, are applicable for analyte specific sensing of small molecules and for multi-analyte detection of biomolecules. For the chemical sensing of small molecules, a sensor chip was functionalized with a molecularly imprinted polymer (MIP). We demonstrate that the MIP receptor layer is compatible with a polymer-based evanescent wave sensor for direct refractive index sensing. For multi-analyte detection of biomolecules, antibody-based receptor layers were patterned by inkjet printing onto the sensor surface demonstrating the applicability of the method with integrated YI chips. Demonstration of the analyte specific chemical- and biosensing with disposable polymeric YI sensor chips opens new possibilities to implement low-cost (bio)chemical sensors.

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Series: RSC advances
ISSN: 2046-2069
ISSN-E: 2046-2069
ISSN-L: 2046-2069
Volume: 6
Pages: 50414 - 50422
DOI: 10.1039/C6RA07320D
Type of Publication: A1 Journal article – refereed
Field of Science: 114 Physical sciences
221 Nanotechnology
Funding: Authors acknowledge financial support by the European Commission via the Seventh Framework Programme under the grant agreement No. 263382 “PHOTOSENS”, and by Academy of Finland grant No. 284907.
Academy of Finland Grant Number: 284907
Detailed Information: 284907 (Academy of Finland Funding decision)
Copyright information: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.