S. Aikio, M. Zeilinger, J. Hiltunen, L. Hakalahti, J. Hiitola-Keinänen, M. Hiltunen, V. Kontturi, S. Siitonen, J. Puustinen, P. Lieberzeit and P. Karioja, RSC Adv., 2016, 6, 50414 DOI: 10.1039/C6RA07320D
Disposable (bio)chemical integrated optical waveguide sensors implemented on roll-to-roll produced platforms
|Author:||Aikio, Sanna1; Zeilinger, Martin2; Hiltunen, Jussi1;|
1VTT Technical Research Centre of Finland, Kaitoväylä 1, Oulu, Finland
2University of Vienna, Faculty for Chemistry, Department of Analytical Chemistry, Währinger Straße 38, 1010 Vienna, Austria
3Nanocomp Oy Ltd, Ensolantie 6, FI-80710 Lehmo, Finland
4University of Oulu, Faculty of Information Technology and Electrical Engineering, Department of Electrical Engineering, Microelectronics and Materials Physics Laboratories, Pentti Kaiteran katu 1, FI-90014 Oulu, Finland
|Online Access:||PDF Full Text (PDF, 1.1 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe201707037611
Royal Society of Chemistry,
|Publish Date:|| 2017-07-03
To enable wide spread dissemination of sensors in cost-critical applications and resource poor settings, methods to implement sensor chips using low-cost materials and mass-manufacturing methods are developed. In this paper we demonstrate that disposable polymeric integrated Young interferometer (YI) sensor chips, implemented on roll-to-roll mass-manufactured waveguides, are applicable for analyte specific sensing of small molecules and for multi-analyte detection of biomolecules. For the chemical sensing of small molecules, a sensor chip was functionalized with a molecularly imprinted polymer (MIP). We demonstrate that the MIP receptor layer is compatible with a polymer-based evanescent wave sensor for direct refractive index sensing. For multi-analyte detection of biomolecules, antibody-based receptor layers were patterned by inkjet printing onto the sensor surface demonstrating the applicability of the method with integrated YI chips. Demonstration of the analyte specific chemical- and biosensing with disposable polymeric YI sensor chips opens new possibilities to implement low-cost (bio)chemical sensors.
|Pages:||50414 - 50422|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
114 Physical sciences
Authors acknowledge financial support by the European Commission via the Seventh Framework Programme under the grant agreement No. 263382 “PHOTOSENS”, and by Academy of Finland grant No. 284907.
|Academy of Finland Grant Number:||
284907 (Academy of Finland Funding decision)
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