University of Oulu

Johanna A. Huhtakangas, Johanna Veijola, Sanna Turunen, Anna Karjalainen, Maarit Valkealahti, Tomi Nousiainen, Susanna Yli-Luukko, Olli Vuolteenaho, Petri Lehenkari, Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis, Data in Brief, Volume 12, 2017, Pages 593-602, ISSN 2352-3409, http://dx.doi.org/10.1016/j.dib.2017.04.041.

Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis

Saved in:
Author: Huhtakangas, Johanna A.1,2; Veijola, Johanna3; Turunen, Sanna1;
Organizations: 1Cancer and Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
2Rheumatology Unit, Department of Medicine, Oulu University Hospital and University of Oulu, Oulu, Finland
3Biochemistry and Molecular Medicine Research Unit, Medical Research Center Oulu, Oulu University, Oulu, Finland
4Division of Operative Care, Oulu University Hospital and University of Oulu, Oulu, Finland
5Biomedicine Unit, Department of Physiology, Medical Research Center Oulu, Oulu University, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe201708168133
Language: English
Published: Elsevier, 2017
Publish Date: 2017-08-16
Description:

Abstract

In this article, we share the raw cytokine data obtained from basal and stimulated synovial stromal cells cultured from patients with rheumatoid arthritis or osteoarthritis. This data article is related to the research article entitled “1,25D₃ and calcipotriol, its hypocalcemic analog, exert a long-lasting anti-inflammatory and anti-proliferative effect in synoviocytes cultured from patients with rheumatoid arthritis and osteoarthritis (1). Cytokine levels were analyzed by a magnetic bead–based multiplex assay (a panel of 27 important cytokines) in two separate sets of experiments. The first was conducted with IL-1β and 1,25(OH)₂D₃ and the other with TNFα, calcipotriol, i.e. the hypocalcemic analog 1,25(OH)₂D₃, and dexamethasone. The raw data of this article display the individual variation in basal secretion of cytokines and in their response to different stimuli.

see all

Series: Data in brief
ISSN: 2352-3409
ISSN-E: 2352-3409
ISSN-L: 2352-3409
Volume: 12
Pages: 593 - 602
DOI: 10.1016/j.dib.2017.04.041
OADOI: https://oadoi.org/10.1016/j.dib.2017.04.041
Type of Publication: A1 Journal article – refereed
Field of Science: 318 Medical biotechnology
3121 Internal medicine
Subjects:
Copyright information: ©2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license
  https://creativecommons.org/licenses/by/4.0/