University of Oulu

Mroueh, R., Haapaniemi, A., Grénman, R., Laranne, J., Pukkila, M., Almangush, A., Salo, T. and Mäkitie, A. (2017), Improved outcomes with oral tongue squamous cell carcinoma in Finland. Head Neck, 39: 1306–1312. doi:10.1002/hed.24744

Improved outcomes with oral tongue squamous cell carcinoma in Finland

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Author: Mroueh, Rayan1; Haapaniemi, Aaro1; Grénman, Reidar2;
Organizations: 1University of Helsinki and Helsinki University Hospital Department of Otorhinolaryngology – Head and Neck Surgery Helsinki Finland
2University of Turku and Turku University Hospital Department of Otorhinolaryngology – Head and Neck Surgery Turku Finland
3Tampere University Hospital Department of Otorhinolaryngology – Head and Neck Surgery Tampere Finland
4Kuopio University Hospital Department of Otorhinolaryngology – Head and Neck Surgery Kuopio Finland
5University of Helsinki Department of Pathology, Haartman Institute Helsinki Finland
6Oulu University Hospital Cancer and Translational Medicine Unit, University of Oulu, Medical Research Unit
7University of Helsinki, and Haartman Institute Oral and Maxillofacial Diseases Helsinki Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.1 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2017120855517
Language: English
Published: John Wiley & Sons, 2017
Publish Date: 2018-05-08
Description:

Abstract

Background: Incidence rates for oral tongue squamous cell carcinoma (SCC) are steadily rising worldwide.

Methods: All patients diagnosed with primary oral tongue SCC at the 5 university hospitals in Finland from 2005 to 2009 were studied. The mean follow-up time was 43 months (median, 54 months; range, 0–111 months).

Results: Three hundred sixty patients with primary oral tongue SCC were identified. Treatment with curative intent was provided for 328 patients (91%). The 5-year disease-specific survival (DSS) rates were as follows: stage I 87%; stage II 73%; stage III 69%; and stage IV 51%. The 5-year recurrence-free survival in general has improved from 47% in our previous published series (1995–1999) to 65% in the current series (p < .001).

Conclusions: The outcome of oral tongue SCC has significantly improved in Finland. However, the relatively high number of disease recurrences in patients with stage I and II disease, when compared with patients with stage III and IV disease, calls for an investigation of new treatment approaches.

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Series: Head & neck
ISSN: 1043-3074
ISSN-E: 1097-0347
ISSN-L: 1043-3074
Volume: 39
Issue: 7
Pages: 1306 - 1312
DOI: 10.1002/hed.24744
OADOI: https://oadoi.org/10.1002/hed.24744
Type of Publication: A1 Journal article – refereed
Field of Science: 3122 Cancers
Subjects:
Copyright information: © 2017 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Mroueh, R., Haapaniemi, A., Grénman, R., Laranne, J., Pukkila, M., Almangush, A., Salo, T. and Mäkitie, A. (2017), Improved outcomes with oral tongue squamous cell carcinoma in Finland. Head Neck, 39: 1306–1312. doi:10.1002/hed.24744, which has been published in final form at https://doi.org/10.1002/hed.24744. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.