Tuomas Viren, Juuso T. Honkanen, Elvis K. Danso, Lassi Rieppo, Rami K. Korhonen, Juha Töyräs, Ultrasound Assessment of Human Meniscus, In Ultrasound in Medicine & Biology, Volume 43, Issue 9, 2017, Pages 1753-1763, ISSN 0301-5629, https://doi.org/10.1016/j.ultrasmedbio.2017.01.020. (http://www.sciencedirect.com/science/article/pii/S0301562917300492) Keywords: Quantitative ultrasound imaging; Osteoarthritis; Composition; Meniscus
Ultrasound assessment of human meniscus
|Author:||Viren, Tuomas1,2; Honkanen, Juuso T.1,3; Danso, Elvis K.1,3;|
1Department of Applied Physics, University of Eastern Finland, Kuopio, Finland
2Cancer Center, Kuopio University Hospital, Kuopio, Finland
3Diagnostic Imaging Center, Kuopio University Hospital, Kuopio Finland
4Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2017121155669
|Publish Date:|| 2018-06-23
The aim of the present study was to evaluate the applicability of ultrasound imaging to quantitative assessment of human meniscus in vitro. Meniscus samples (n = 26) were harvested from 13 knee joints of non-arthritic human cadavers. Subsequently, three locations (anterior, center and posterior) from each meniscus were imaged with two ultrasound transducers (frequencies 9 and 40 MHz), and quantitative ultrasound parameters were determined. Furthermore, partial-least-squares regression analysis was applied for ultrasound signal to determine the relations between ultrasound scattering and meniscus integrity. Significant correlations between measured and predicted meniscus compositions and mechanical properties were obtained (R² = 0.38–0.69, p < 0.05). The relationship between conventional ultrasound parameters and integrity of the meniscus was weaker. To conclude, ultrasound imaging exhibited a potential for evaluation of meniscus integrity. Higher ultrasound frequency combined with multivariate analysis of ultrasound backscattering was found to be the most sensitive for evaluation of meniscus integrity.
Ultrasound in medicine & biology
|Pages:||1753 - 1763|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
217 Medical engineering
3126 Surgery, anesthesiology, intensive care, radiology
Financial support from the Sigrid Juselius Foundation, strategic funding of the University of Eastern Finland, National Doctoral Programme of Musculoskeletal Disorders and Biomaterials (TBDP), Kuopio University Hospital (VTR projects 1V276, 1V090 and 5654156) and Academy of Finland (projects 267551 and 269315) are acknowledged.
© 2017 World Federation for Ultrasound in Medicine & Biology Printed in the USA. All rights reserved.