University of Oulu

Appl. Sci. 2019, 9, 217; doi:10.3390/app9020217

Fiber-optic system for intraoperative study of abdominal organs during minimally invasive surgical interventions

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Author: Kandurova, Ksenia1; Dremin, Viktor1; Zherebtsov, Evgeny1,2;
Organizations: 1Orel State University, Research and Development Center of Biomedical Photonics, 302026 Orel, Russia
2University of Oulu, 90014 Oulu, Finland
3Orel Regional Clinical Hospital, 302028 Orel, Russia
4Federal Scientific and Clinical Center for Specialized Medical Service and Medical Technologies, 115682 Moscow, Russia
5Problem Research Laboratory “Diagnostic Researches and Mini-invasive Technologies”, Smolensk State Medical University, 214019 Smolensk, Russia
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.7 MB)
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Language: English
Published: Multidisciplinary Digital Publishing Institute, 2019
Publish Date: 2019-04-10


The paper presents the results of experimental measurements of endogenous fluorescence and blood perfusion in patients with pathology of the organs of hepatopancreatoduodenal area in vivo. A custom setup combining channels for fluorescence spectroscopy (excitation wavelengths of 365 nm and 450 nm) and laser Doppler flowmetry (1064 nm) with fibre optical probe for nondestructive laparoscopic measurements has been developed and applied during minimally invasive operation procedure. Preliminary measurements with two aforementioned channels have been performed at specified excitation wavelengths. The possibility of obtaining fluorescence spectra and laser Doppler flowmetry signals in vivo during minimally invasive interventions was shown. Obtained data show perspectives of further research on technical and methodological development of optical diagnostic methods for minimally invasive surgery. The obtained results can be used to provide a deeper understanding of pathological processes influence on optical properties of abdominal organs tissues, which will ultimately help surgeons to determine the state of vitality in tissues and mucous membranes directly during the process of surgical intervention.

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Series: Applied sciences
ISSN: 2076-3417
ISSN-E: 2076-3417
ISSN-L: 2076-3417
Volume: 9
Issue: 2
Article number: 217
DOI: 10.3390/app9020217
Type of Publication: A1 Journal article – refereed
Field of Science: 217 Medical engineering
213 Electronic, automation and communications engineering, electronics
Funding: This research was funded by the Russian Science Foundation under grant number 18-15-00201.
Copyright information: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (