University of Oulu

Evgeny A. Zherebtsov, Angelina I. Zherebtsova, Alexander Doronin, Andrey Dunaev, Konstantin V. Podmasteryev, Alexander Bykov, Igor Meglinski, "Combined use of laser Doppler flowmetry and skin thermometry for functional diagnostics of intradermal finger vessels," J. Biomed. Opt. 22(4) 040502 (11 April 2017). doi: 10.1117/1.JBO.22.4.040502

Combined use of laser Doppler flowmetry and skin thermometry for functional diagnostics of intradermal finger vessels

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Author: Zherebtsov, Evgeny A.1,2; Zherebtsova, Angelina I.1; Doronin, Alexander3;
Organizations: 1Orel State University, Scientific-Educational Centre of Biomedical Engineering, Biomedical Photonics Instrumentation Group, Orel, Russia
2University of Oulu, ITEE, Optoelectronics and Measurement Techniques Unit, Oulu, Finland
3Yale University, Department of Computer Science, Computer Graphics Group, New Haven, Connecticut, United States
4Tomsk State University, Interdisciplinary Laboratory of Biophotonics, Tomsk, Russia
5ITMO University, Saint-Petersburg, Russia
6Irkutsk State University, Institute of Biology, Irkutsk, Russia
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.2 MB)
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Language: English
Published: SPIE, 2017
Publish Date: 2019-04-15


We introduce a noninvasive diagnostic approach for functional monitoring of blood microflows in capillaries and thermoregulatory vessels within the skin. The measuring system is based on the combined use of laser Doppler flowmetry and skin contact thermometry. The obtained results suggest that monitoring of blood microcirculation during the occlusion, performed in conjunction with the skin temperature measurements in the thermally stabilized medium, has a great potential for quantitative assessment of angiospatic dysfunctions of the peripheral blood vessels. The indices of blood flow reserve and temperature response were measured and used as the primarily parameters of the functional diagnostics of the peripheral vessels of skin. Utilizing these parameters, a simple phenomenological model has been suggested to identify patients with angiospastic violations in the vascular system.

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Series: Journal of biomedical optics
ISSN: 1083-3668
ISSN-E: 1560-2281
ISSN-L: 1083-3668
Volume: 22
Issue: 4
Article number: 040502
DOI: 10.1117/1.JBO.22.4.040502
Type of Publication: A1 Journal article – refereed
Field of Science: 217 Medical engineering
213 Electronic, automation and communications engineering, electronics
Funding: The work was supported by a grant from the President of the Russian Federation for state support of young Russian scientists No. MK-7168.2016.8. The authors acknowledge the support of the Academy of Finland (Grant Nos: 296408 and 290596). Professor Meglinski also acknowledges partial support provided by the Russian Science Foundation project No. 15-14-10008.
Academy of Finland Grant Number: 296408
Detailed Information: 296408 (Academy of Finland Funding decision)
290596 (Academy of Finland Funding decision)
Copyright information: © 2017 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.22.4.040502]