Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, "Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo," J. Biomed. Opt. 22(11) 110504 (20 November 2017). http://dx.doi.org/10.1117/1.JBO.22.11.110504
Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo
|Author:||Popov, Alexey P.1,2; Bykov, Alexander V.1,2; Meglinski, Igor V.1,2,3,4|
1University of Oulu, Opto-Electronics and Measurement Techniques Research Unit, Faculty of Information Technology and Electrical Engineering, Oulu, Finland
2ITMO University, International Institute of Photonics and Optoinformatics, St. Petersburg, Russia
3Irkutsk State University, Institute of Biology, Irkutsk, Russia
4National Research Nuclear University “MEPhI,” Institute of Engineering Physics for Biomedicine (PhysBio), Moscow, Russia
|Online Access:||PDF Full Text (PDF, 2.1 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2019043013666
|Publish Date:|| 2019-04-30
Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.
Journal of biomedical optics
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
217 Medical engineering
318 Medical biotechnology
The Academy of Finland (grants 260321 and 290596), the Russian Science Foundation (project 15-14-10008), MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005), and the Government of Russian Federation (Grant No. 074-U01) are acknowledged for financial support.
|Academy of Finland Grant Number:||
260321 (Academy of Finland Funding decision)
290596 (Academy of Finland Funding decision)
© 2017 SPIE. Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in t his paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/1.JBO.22.11.110504.