Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo
Popov, Alexey P.; Bykov, Alexander V.; Meglinski, Igor V. (2017-11-20)
Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, "Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo," J. Biomed. Opt. 22(11) 110504 (20 November 2017). http://dx.doi.org/10.1117/1.JBO.22.11.110504
© 2017 SPIE. Society of Photo-Optical Instrumentation Engineers and Optical Society of America. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in t his paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/1.JBO.22.11.110504.
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https://urn.fi/URN:NBN:fi-fe2019043013666
Tiivistelmä
Abstract
Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.
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