University of Oulu

Parra, G.R., Smith, G.L., Mason, W.A. et al. J Child Fam Stud (2018) 27: 717.

Profiles of contextual risk at birth and adolescent substance use

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Author: Parra, Gilbert R.1; Smith, Gail L.2; Mason, W. Alex2;
Organizations: 1Department of Child, Youth and Family Studies, University of Nebraska-Lincoln, Lincoln, USA
2Boys Town National Research Institute for Child and Family Studies, Boys Town, USA
3Institute for Social Research, University of Michigan, ICPSR, Ann Arbor, USA
4Center for Life Course Health Research, University of Oulu, Oulu, Finland
5Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
6Department of Epidemiology and Biostatistics, MRC PHE Centre for Environment and Health, School of Public Health, Imperial College, London, UK
7PEDEGO Research Center, University of Oulu, Oulu, Finland
8Department of Child Psychiatry, Oulu University Hospital, Oulu, Finland
9Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland
10Department of Psychiatry, University Hospital of Oulu, Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
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Language: English
Published: Springer Nature, 2017
Publish Date: 2019-05-14


This study examined whether there are subgroups of families with distinct profiles of prenatal/birth contextual risk, and whether subgroup membership was differentially related to adolescent substance use. Data from the Northern Finland Birth Cohort 1986 were used. A five-class model provided the most meaningful solution. Large Family Size (7.72%) and Low Risk (69.69%) groups had the lowest levels of alcohol, cigarette, and illegal drug use. Similar high levels for each of the three substance-related outcomes were found for Parent Substance Misuse (11.20%), Maternal School Dropout (4.66%), and Socioeconomic Disadvantage (6.72%) groups. Maternal smoking and drinking while pregnant and paternal heavy alcohol use were found to be key prenatal risk factors that tended to cluster together and co-occur with other prenatal risk factors differently for different subgroups of youth.

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Series: Journal of child and family studies
ISSN: 1062-1024
ISSN-E: 1573-2843
ISSN-L: 1062-1024
Volume: 27
Issue: 3
Pages: 717 - 724
DOI: 10.1007/s10826-017-0935-x
Type of Publication: A1 Journal article – refereed
Field of Science: 3124 Neurology and psychiatry
3123 Gynaecology and paediatrics
Funding: The analyses were supported by National Institute on Drug Abuse (NIDA), National Institutes of Health, Grant # R01 DA038450. NFBC1986 has received support from the Academy of Finland (#268336), the European Commission (EURO-BLCS, Framework 5 award QLG1-CT-2000-01643), the H2020-633595 DynaHEALTH action and academy of Finland EGEA-project, and the US National Institutes of Health (NIMH) (5R01MH63706:02). The preparation of this manuscript was also supported by the Institute of Education Sciences (IES), U.S. Department of Education, through Grant R324B110001. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies. The funders played no role in the research design, data collection, analysis, or writing and submission process.
EU Grant Number: (633595) DYNAHEALTH - Understanding the dynamic determinants of glucose homeostasis and social capability to promote Healthy and active aging
Academy of Finland Grant Number: 268336
Detailed Information: 268336 (Academy of Finland Funding decision)
Copyright information: © Springer Science+Business Media, LLC 2017. This is a post-peer-review, pre-copyedit version of an article published in Journal of Child and Family Studies. The final authenticated version is available online at: