University of Oulu

Patwardhan, I., Mason, W. A., Savolainen, J., Chmelka, M. B., Miettunen, J., & Järvelin, M.-R. (2017). Childhood cumulative contextual risk and depression diagnosis among young adults: The mediating roles of adolescent alcohol use and perceived social support. Journal of Adolescence, 60, 16–26. https://doi.org/10.1016/j.adolescence.2017.07.008

Childhood cumulative contextual risk and depression diagnosis among young adults : the mediating roles of adolescent alcohol use and perceived social support

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Author: Patwardhan, Irina1; Mason, W. Alex1; Savolainen, Jukka2;
Organizations: 1Boys Town National Research Institute for Child and Family Studies, 14100 Crawford Street, Boys Town, NE, 68010, USA
2Institute for Social Research, University of Michigan, ICPSR, Ann Arbor, MI, USA
3Center for Life Course Epidemiology and Systems Medicine, University of Oulu, Oulu, Finland
4Medical Research Center Oulu, Oulu University Hospital, University of Oulu, Oulu, Finland
5Department of Psychiatry, Unit for Clinical Neuroscience, University of Oulu, Finland
6Department of Epidemiology and Biostatistics, MRC PHE Centre for Environment and Health, School of Public Health, Imperial College London, UK
7Center for Life Course Epidemiology, Faculty of Medicine, P.O. Box 5000, FI-90014, University of Oulu, Finland
8Unit of Primary Care, Oulu University Hospital, Oulu, Finland
Format: article
Version: accepted version
Access: embargoed
Persistent link: http://urn.fi/urn:nbn:fi-fe2019051515585
Language: English
Published: Elsevier, 2017
Publish Date: 2020-07-24
Description:

Abstract

This study examined associations between cumulative contextual risk in childhood and depression diagnosis in early adulthood, testing two adolescent mediating mechanisms, alcohol use and perceived social support from family and friends, while accounting for the stability of internalizing problems over time and examining possible gender moderation. Multiple group mediation analyses were conducted using parent- and adolescent-report as well as hospital records data from the Northern Finland Birth Cohort 1986 (N = 6963). Our analyses demonstrated that the association between cumulative contextual risk in childhood and depression diagnosis in adulthood is mediated by adolescent alcohol use and perceived social support both for boys and girls. The findings highlight potentially malleable mediating mechanisms associated with depression in vulnerable youth that could be targets in selective depression preventive interventions.

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Series: Journal of adolescence
ISSN: 0140-1971
ISSN-E: 1095-9254
ISSN-L: 0140-1971
Volume: 60
Pages: 16 - 26
DOI: 10.1016/j.adolescence.2017.07.008
OADOI: https://oadoi.org/10.1016/j.adolescence.2017.07.008
Type of Publication: A1 Journal article – refereed
Field of Science: 3124 Neurology and psychiatry
Subjects:
Funding: The analyses were supported by National Institute on Drug Abuse (NIDA), National Institutes of Health, Grant # R01 DA038450. Support for the Northern Finland Birth Cohort was provided by the European Commission (Grant DynaHEALTH—H2020—633595), EU QLG1-CT-2000-01643 (EUROBLCS) Grant no. E51560, NorFA Grant no. 731, 20056, 30167, and USA/NIHH 2000 G DF682 Grant no. 50945. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding agencies.
EU Grant Number: (633595) DYNAHEALTH - Understanding the dynamic determinants of glucose homeostasis and social capability to promote Healthy and active aging
Copyright information: © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http:/creativecommons.org/licenses/by-nc-nd/4.0/
  https://creativecommons.org/licenses/by-nc-nd/4.0/