Intellectual disability in patients with epilepsy with eyelid myoclonias |
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Author: | Arvio, Maria1,2,3; Sauna-aho, Oili2,4; Nyrke, Timo1; |
Organizations: |
1Joint Authority for Päijät-Häme Social and Health Care, Lahti, Finland 2Department of Child Neurology, Turku University Hospital, Turku, Finland 3PEDEGO, Oulu University Hospital, Oulu, Finland
4Southwest Special Care Municipal Authority, Paimio, Finland
5Tampere University Hospital, Tampere, Finland |
Format: | article |
Version: | published version |
Access: | open |
Online Access: | PDF Full Text (PDF, 0.1 MB) |
Persistent link: | http://urn.fi/urn:nbn:fi-fe2019062021454 |
Language: | English |
Published: |
SAGE Publications,
2018
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Publish Date: | 2019-06-20 |
Description: |
AbstractWe describe here the clinical outcome of four women with epilepsy with eyelid myoclonia (aged 21–53 years). All patients had an uneventful early history, normal physical growth and appearance and no comorbid sensory or motor disability and normal brain magnetic resonance imaging finding. Two women were moderately and one mildly intellectually disabled and one showed a low-average intelligence. The overall well-being of the patients was hampered by psychiatric or various somatic comorbidities and related psychosocial problems. The three women with an intellectual disability had been treated with narrow-spectrum antiepileptic drugs and one also with vigabatrin during childhood and adolescence. The patient with a low-average intelligence had been on broad-spectrum antiepileptic medication (i.e. valproate and ethosuximide) since the epilepsy diagnosis but she has had compliance problems. Based on these cases, the cognitive deficits in patients with epilepsy with eyelid myoclonia may occur more commonly than what has been thought hitherto. We discuss the role of narrow-spectrum antiepileptic drugs as a contributing factor to poor seizure control and an impaired intelligence. see all
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Series: |
SAGE open medical case reports |
ISSN: | 2050-313X |
ISSN-E: | 2050-313X |
ISSN-L: | 2050-313X |
Volume: | 6 |
Pages: | 1 - 4 |
DOI: | 10.1177/2050313X18777951 |
OADOI: | https://oadoi.org/10.1177/2050313X18777951 |
Type of Publication: |
A1 Journal article – refereed |
Field of Science: |
3124 Neurology and psychiatry |
Subjects: | |
Funding: |
The author(s) received no financial support for the research, authorship and/or publication of this article. |
Copyright information: |
© The Author(s) 2018. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
https://creativecommons.org/licenses/by-nc/4.0/ |