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Association between periodontal condition and the development of type 2 diabetes mellitus : results from a 15-year follow-up study |
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| Author: | Myllymäki, Ville1; Saxlin, Tuomas1,2,3; Knuuttila, Matti4,5; |
| Organizations: |
1Institute of Dentistry, University of Eastern Finland, Kuopio, Finland 2Department of Oral and Maxillofacial Diseases, Kuopio University Hospital, Kuopio, Finland 3Research Unit of Oral Health Sciences, University of Oulu, Oulu, Finland
4Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
5Department of Oral and Maxillofacial Surgery, Oulu University Hospital, Oulu, Finland 6Center for Life Course Health Research, University of Oulu, Oulu, Finland 7Unit of Primary Health Care, Oulu University Hospital, Oulu, Finland 8Teaching Health Centre, City of Oulu, Finland |
| Format: | article |
| Version: | accepted version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 0.8 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2019070422793 |
| Language: | English |
| Published: |
John Wiley & Sons,
2018
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| Publish Date: | 2019-11-30 |
| Description: |
AbstractAim: To study whether periodontal condition is associated with the development of type 2 diabetes mellitus (T2DM). Materials and Methods: A population‐based follow‐up study was conducted among persons born in 1935 and living in the city of Oulu, Finland (n = 395). The baseline examinations were done during 1990–1992, and the follow‐up examinations were done during 2007–2008. The data were gathered by questionnaires, laboratory tests and clinical measurements. Poisson regression models were used in the data analyses. Results: The adjusted rate ratios (RR) with 95% confidence intervals (95% CI) for the incident T2DM among subjects with 4–5 mm deep periodontal pockets (n = 98), among subjects with 6 mm deep or deeper periodontal pockets (n = 91), and among edentulous subjects (n = 118) were 1.32 (95% CI: 0.69–2.53), 1.56 (95% CI: 0.84–2.92) and 1.00 (95% CI: 0.53–1.89), respectively, compared to dentate subjects without deepened (4 mm deep or deeper) periodontal pockets (n = 88). The adjusted RR per site (the number of sites with deepened periodontal pockets as a continuous variable) was 1.02 (95% CI: 1.00–1.04). Conclusions: Poor periodontal condition may be a predictor of the development of T2DM. However, the causality between periodontal condition and the development of T2DM remains uncertain. see all
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| Series: |
Journal of clinical periodontology |
| ISSN: | 0303-6979 |
| ISSN-E: | 1600-051X |
| ISSN-L: | 0303-6979 |
| Volume: | 45 |
| Issue: | 11 |
| Pages: | 1276 - 1286 |
| DOI: | 10.1111/jcpe.13005 |
| OADOI: | https://oadoi.org/10.1111/jcpe.13005 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
313 Dentistry |
| Subjects: | |
| Copyright information: |
© 2018 John Wiley & Sons A/S. This is the peer reviewed version of the following article: Myllymäki, V, Saxlin, T, Knuuttila, M, et al. Association between periodontal condition and the development of type 2 diabetes mellitus—Results from a 15‐year follow‐up study. J Clin Periodontol. 2018; 45: 1276– 1286. https://doi.org/10.1111/jcpe.13005, which has been published in final form at https://doi.org/10.1111/jcpe.13005. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. |