University of Oulu

Ushenko, V. A.; Sdobnov, A. Yu.; Mishalov, W. D.; Dubolazov, A. V.; Olar, O. V.; Bachinskyi, V. T.; Ushenko, A. G.; Ushenko, Yu. A.; Wanchuliak, O. Ya.; Meglinski, I. (2019) Biomedical applications of Jones-matrix tomography to polycrystalline films of biological fluids, Journal of Innovative Optical Health Sciences, 12(6): 1950017,

Biomedical applications of Jones-matrix tomography to polycrystalline films of biological fluids

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Author: Ushenko, V. A.1; Sdobnov, A. Yu.2; Mishalov, W. D.3;
Organizations: 1Chernivtsi National University, 2 Kotsiubynskyi St., Chernivtsi, 58012 Ukraine
2Faculty of Information Technology and Electrical Engineering University of Oulu, Oulu 90570, Finland
3Shupyk National Medical Academy of Postgraduate Education 9, Dorogozhytska St., Kyiv, 04112 Ukraine
4Chernivtsi National University 2 Kotsiubynskyi St., Chernivtsi, 58012 Ukraine
5Aston Institute of Materials Research School of Engineering and Applied Science Aston University, Birmingham, B4 7ET, UK
6Bukovinian State Medical University 3 Theatral Sq., Chernivtsi, 58000 Ukraine
7Interdisciplinary Laboratory of Biophotonics National Research Tomsk State University Tomsk, 634050 Russia
8nstitute of Engineering Physics for Biomedicine (PhysBio) National Research Nuclear University \ MEPhI " Moscow, 15409 Russia
9School of Life and Health Sciences, Aston University Birmingham, B4 7ET, UK
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 3.9 MB)
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Language: English
Published: World Scientific, 2019
Publish Date: 2019-08-15


Algorithms for reconstruction of linear and circular birefringence-dichroism of optically thin anisotropic biological layers are presented. The technique of Jones-matrix tomography of polycrystalline films of biological fluids of various human organs has been developed and experimentally tested. The coordinate distributions of phase and amplitude anisotropy of bile films and synovial fluid taken from the knee joint are determined and statistically analyzed. Criteria (statistical moments of 3rd and 4th orders) of differential diagnostics of early stages of cholelithiasis and septic arthritis of the knee joint with excellent balanced accuracy were determined. Data on the diagnostic efficiency of the Jones-matrix tomography method for polycrystalline plasma (liver disease), urine (albuminuria) and cytological smears (cervical cancer) are presented.

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Series: Journal of innovative optical health sciences
ISSN: 1793-5458
ISSN-E: 1793-7205
ISSN-L: 1793-5458
Volume: 12
Issue: 6
Article number: 1950017
DOI: 10.1142/S1793545819500172
Type of Publication: A1 Journal article – refereed
Field of Science: 114 Physical sciences
Funding: Authors acknowledge ̄nancial support of the Academy of Finland (grant projects: 311698). IM acknowledges partial support of INFOTECH grant project, as well as the MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005) and the National Research Tomsk State University Academic D.I. Mendeleev Fund Program.
Academy of Finland Grant Number: 311698
Detailed Information: 311698 (Academy of Finland Funding decision)
Copyright information: © 2019 The Author(s). This is an Open Access article published by World Scienti ̄c Publishing Company. It is distributed under the terms of the Creative Commons Attribution 4.0 (CC BY) License which permits use, distribution and reproduction in any medium, provided the original work is properly cited.