University of Oulu

Ksenia Kandurova, Elena Potapova, Valery Shupletsov, Igor Kozlov, Evgeniya Seryogina, Viktor Dremin, Evgeny Zherebtsov, Alexander Alekseyev M.D., Andrian Mamoshin M.D., and Andrey Dunaev "Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791C (22 July 2019);

Optical fine-needle biopsy approach for intraoperative multimodal diagnostics in minimally invasive abdominal surgery

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Author: Kandurova, Ksenia1; Potapova, Elena1; Shupletsov, Valery1;
Organizations: 1Research and Development Center of Biomedical Photonics, Orel State University, Orel, Russia
2Optoelectronics and Measurement Techniques Unit, University of Oulu, Oulu, Finland
3Orel Regional Clinical Hospital, Orel, Russia
Format: abstract
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.5 MB)
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Language: English
Published: SPIE, 2019
Publish Date: 2019-08-27


The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.

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Series: Proceedings of SPIE
ISSN: 0277-786X
ISSN-E: 1996-756X
ISSN-L: 0277-786X
Volume: 11079
Article number: 110791C
DOI: 10.1117/12.2526747
Host publication: Proceedings, Medical Laser Applications and Laser-Tissue Interactions IX. European Conferences on Biomedical Optics. 23-27 June 2019, Munich, Germany
Conference: European Conferences on Biomedical Optics
Field of Science: 213 Electronic, automation and communications engineering, electronics
217 Medical engineering
3111 Biomedicine
3141 Health care science
Funding: This study was supported by the Russian Science Foundation under project № 18-15-00201.
Copyright information: © 2019 Society of Photo‑Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited.