University of Oulu

Tikanmäki, M., Tammelin, T., Vääräsmäki, M., Sipola-Leppänen, M., Miettola, S., Pouta, A., … Kajantie, E. (2017). Prenatal determinants of physical activity and cardiorespiratory fitness in adolescence – Northern Finland Birth Cohort 1986 study. BMC Public Health, 17(1). https://doi.org/10.1186/s12889-017-4237-4

Prenatal determinants of physical activity and cardiorespiratory fitness in adolescence : Northern Finland birth cohort 1986 study

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Author: Tikanmäki, Marjaana1,2; Tammelin, Tuija3; Vääräsmäki, Marja4,5;
Organizations: 1Chronic Disease Prevention Unit, Department of Health, National Institute for Health and Welfare, Oulu and Helsinki, Finland
2Institute of Health Sciences, University of Oulu, Oulu, Finland
3LIKES Research Center for Physical Activity and Health, Jyväskylä, Finland
4Pediatrics and Adolescence and Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
5Children, Adolescents and Families Unit, Department of Welfare, National Institute for Health and Welfare, Oulu, Finland
6Department of Government Services, National Institute for Health and Welfare, Helsinki, Finland
7Department of Epidemiology and Biostatistics, MRC–PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, UK
8Center for Life Course Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland
9Biocenter Oulu, Oulu, Finland
10Unit of Primary Care, Oulu University Hospital, Oulu, Finland
11Children’s Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.9 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2019082825950
Language: English
Published: Springer Nature, 2017
Publish Date: 2019-08-28
Description:

Abstract

Background: Lower levels of physical activity and cardiorespiratory fitness are key risk factors of chronic adult diseases. Physical activity and cardiorespiratory fitness are predicted by birth weight, but the underlying parental and pregnancy-related factors remain largely unknown. We examined how prenatal determinants are associated with physical activity and cardiorespiratory fitness in adolescence.

Methods: Of the 16-year-old members of the population-based Northern Finland Birth Cohort 1986 (NFBC 1986), 6682 singletons with no major physical disability reported their amount of physical activity outside school hours, and 4706 completed a submaximal cycle ergometer test assessing cardiorespiratory fitness. Physical activity was expressed as metabolic equivalent hours per week (METh/week) and cardiorespiratory fitness as peak oxygen uptake (ml·kg−1·min−1). Prenatal determinants included birth weight, length of gestation, mother’s and father’s body mass index (BMI), maternal gestational diabetes mellitus (GDM), and maternal hypertension and smoking during pregnancy. Data were analyzed by multiple linear regression.

Results: A higher birth weight and longer length of gestation predicted lower levels of physical activity and cardiorespiratory fitness at 16 years, although the association between length of gestation and physical activity was inverse U-shaped. Mother’s or father’s overweight or obesity before pregnancy were associated with lower levels of their offspring’s physical activity and fitness in adolescence. Adjusting for maternal pregnancy disorders and the adolescent’s own BMI attenuated the associations with the mother’s but not the father’s overweight/obesity. Furthermore, maternal GDM predicted lower cardiorespiratory fitness.

Conclusions: A high birth weight and parental overweight/obesity are associated with lower levels of both physical activity and cardiorespiratory fitness in adolescence, while maternal GDM and longer length of gestation are associated with lower cardiorespiratory fitness. Both long and short lengths of gestation predict low physical activity.

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Series: BMC public health
ISSN: 1471-2458
ISSN-E: 1471-2458
ISSN-L: 1471-2458
Volume: 17
Article number: 346
DOI: 10.1186/s12889-017-4237-4
OADOI: https://oadoi.org/10.1186/s12889-017-4237-4
Type of Publication: A1 Journal article – refereed
Field of Science: 3142 Public health care science, environmental and occupational health
Subjects:
Funding: The study was supported by grants from the Academy of Finland (SALVE program for 2009–2012 and grants 127,437, 129,306, 130,326, 134,791 and 263,924 to EK), Doctoral Programme for Public Health, University of Tampere (to MSL), Emil Aaltonen Foundation (to EK), European Commission (Framework 5 award QLG1-CT-2000-001643 to MRJ), Finnish Foundation for Pediatric Research (to EK), Finnish Medical Society, Duodecim (to EK), Jalmari and Rauha Ahokas Foundation (EK), Juho Vainio Foundation (EK, MSL, MT,), The National Graduate School of Clinical Investigation (to MT), Novo Nordisk Foundation (to EK, MV,), Signe and Ane Gyllenberg Foundation (to EK), Sigrid Jusélius Foundation (to EK), and Yrjö Jahnsson Foundation (EK, MSL, MV). The funders had no role in the design of the study and collection, analysis and interpretation of data or in writing the manuscript.
Copyright information: © The Author(s). 2017. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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