University of Oulu

Thevenot J., Hirvasniemi J., Finnilä M., Lehenkari P., Saarakkala S. (2018) Volumetric Assessment of Bone Microstructures by a 3D Local Binary Patterns –Based Method: Bone Changes with Osteoarthritis. In: Eskola H., Väisänen O., Viik J., Hyttinen J. (eds) EMBEC & NBC 2017. EMBEC 2017, NBC 2017. IFMBE Proceedings, vol 65. Springer, Singapore

Volumetric assessment of bone microstructures by a 3D local binary patterns – based method: bone changes with osteoarthritis

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Author: Thevenot, Jérôme1; Hirvasniemi, Jukka1; Finnilä, Mikko1,2;
Organizations: 1University of Oulu, Oulu, Finland
2University of Eastern Finland, Kuopio, Finland
3Oulu University Hospital, Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2019090426592
Language: English
Published: Springer Nature, 2017
Publish Date: 2019-09-04
Description:

Abstract

Osteoarthritis (OA) causes progressive degeneration of articular cartilage and pathological changes in subchondral bone, conventionally assessed volumetrically using micro-computed tomography (μCT) imaging in vitro. The local binary patterns (LBP) method has recently been suggested as a new alternative solution to perform analysis of local bone structures from μCT scans. In this study, a novel 3D LBP-based method to provide a new lead in bone microstructural analysis is proposed. In addition to the detailed description of the method, this solution is tested using µCT data of OA human trabecular bone samples, harvested from patients treated with total knee arthroplasty. The method was applied to correlate the distribution of orientations of local patterns with the severity of the disease. The local orientations of the bone fibers changed along the severity of OA, suggesting an adaptation of the bone to the disease. The structural parameters derived from the process were able to provide a new approach for the assessment of the disease, supporting the potential of this volumetric LBP-based method to assess trabecular bone changes.

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Series: IFMBE proceedings
ISSN: 1680-0737
ISSN-E: 1433-9277
ISSN-L: 1680-0737
ISBN: 978-981-10-5122-7
ISBN Print: 978-981-10-5121-0
Pages: 900 - 903
DOI: 10.1007/978-981-10-5122-7_225
OADOI: https://oadoi.org/10.1007/978-981-10-5122-7_225
Host publication: EMBEC & NBC 2017. Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), Tampere, Finland, June 2017
Host publication editor: Eskola, Hannu
Väisänen, Outi
Viik, Jari
Hyttinen, Jari
Conference: European Medical and Biological Engineering Conference (EMBEC). Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC)
Type of Publication: A4 Article in conference proceedings
Field of Science: 217 Medical engineering
Subjects:
LBP
Funding: This study was supported by Infotech Oulu, the Academy of Finland, the European Research Council (ERC grant no. 336267) and the strategic funding of the University of Oulu.
EU Grant Number: (336267) 3D-OA-HISTO - Development of 3D Histopathological Grading of Osteoarthritis
Copyright information: © Springer Nature Singapore Pte Ltd. 2018. This is a post-peer-review, pre-copyedit version of an article published in EMBEC & NBC 2017. Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), Tampere, Finland, June 2017. The final authenticated version is available online at: https://doi.org/10.1007/978-981-10-5122-7_225.