Heikkilä, P., Sokuri, P., Mecklin, M., Nuolivirta, K., Tapiainen, T., Peltoniemi, O., … Korppi, M. (2018). Using high-flow nasal cannulas for infants with bronchiolitis admitted to paediatric wards is safe and feasible. Acta Paediatrica, 107(11), 1971–1976. https://doi.org/10.1111/apa.14421
Using high-flow nasal cannulas for infants with bronchiolitis admitted to paediatric wards is safe and feasible
|Author:||Heikkilä, Paula1; Sokuri, Paula1; Mecklin, Minna1;|
1Centre for Child Health Research, Tampere University and University Hospital, Tampere, Finland
2Department of Paediatrics, Seinäjoki Central Hospital, Seinäjoki, Finland
3Department of Paediatrics, Oulu University Hospital, and PEDEGO Research Centre, Oulu University
|Online Access:||PDF Full Text (PDF, 0.2 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2019090426614
John Wiley & Sons,
|Publish Date:|| 2019-09-04
Aim: Using a high‐flow nasal cannula (HFNC) for infant bronchiolitis is increasingly common, but insufficiently studied. In this retrospective study, we examined the outcomes of HFNC and compared infants who did and did not respond to this oxygen delivery method.
Methods: This 2012–2015 study of six Finnish hospitals focused on 88 infants under 12 months who received HFNC: 53 on paediatric wards and 35 in paediatric intensive care units (PICUs). We reviewed patient files for underlying factors, clinical parameters and HFNC treatment. The treatment failed if the patient was transferred to another respiratory support.
Results: We found HFNC treatment was successful in 76 (86%) infants, including all 53 on the paediatric wards and 23/35 PICU patients. The responders’ heart rates were significantly lower, and their oxygen saturation was significantly higher at 60 minutes after HFNC treatment started and then stayed relatively constant. Their respiratory rate was only significantly lower after 360 minutes. In non‐responders, the respiratory rate initially decreased but was higher at 180 and 360 minutes after the start of HFNC.
Conclusion: We found preliminary evidence that oxygen support needs and heart rate were useful early predictors of HFNC therapy success in infants hospitalised with bronchiolitis, but respiratory rate was not.
|Pages:||1971 - 1976|
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3123 Gynaecology and paediatrics
3121 General medicine, internal medicine and other clinical medicine
This study was funded by the Tampere Tuberculosis Foundation.
© 2018 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd 2018. This is the peer reviewed version of the following article: Heikkilä, P., Sokuri, P., Mecklin, M., Nuolivirta, K., Tapiainen, T., Peltoniemi, O., … Korppi, M. (2018). Using high-flow nasal cannulas for infants with bronchiolitis admitted to paediatric wards is safe and feasible. Acta Paediatrica, 107(11), 1971–1976. https://doi.org/10.1111/apa.14421, which has been published in final form at https://doi.org/10.1111/apa.14421. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.