University of Oulu

Michael Aschner, Herman Autrup, Colin L. Berry, Alan R. Boobis, Samuel M. Cohen, Wolfgang Dekant, Corrado L. Galli, Jay I. Goodman, Gio B. Gori, Helmut A. Greim, Norbert E. Kaminski, Curtis D. Klaassen, James E. Klaunig, Marcello Lotti, Hans WJ. Marquardt, Angelo Moretto, Olavi Pelkonen, I. Glenn Sipes, Kendall B. Wallace, Hiroshi Yamazaki, Obfuscating transparency?, Regulatory Toxicology and Pharmacology, Volume 97, 2018, Pages A1-A3, ISSN 0273-2300, https://doi.org/10.1016/j.yrtph.2018.07.004

Obfuscating transparency?

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Author: Aschner, Michael1; Autrup, Herman2; Berry, Colin L.3;
Organizations: 1Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY, USA
2Institute of Public Health, University of Aarhus, Aarhus, Denmark
3Emeritus of Pathology, Queen Mary, London, UK
4Department of Medicine, Imperial College London, London, UK
5Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA
6Department of Toxicology, University of Wuerzburg, Wuerzburg, Germany
7Toxicology and Risk Assessment, Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
8Pharmacology & Toxicology Department, Michigan State University East Lansing, MI, USA
9The Health Policy Center, Editor, Regulatory Toxicology and Pharmacology, Bethesda, MD, USA
10Technical University of Munich, Munich, Germany
11Pharmacology & Toxicology, Director, Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, USA
12Department of Pharmacology, Toxicology and Therapeutics, College of Medicine, University of Kansas, Kansas City, KS, USA
13Department of Environmental Health, School of Public Health, Indiana University Bloomington, IN, USA
14Department of Cardiology, Thoracic and Vascular Sciences, School of Medicine, University of Padua, Padua, Italy
15Experimental and Clinical Toxicology, University of Hamburg Medical School, Hambug, Germany
16Department of, Biomedical and Clinical Sciences, University of Milan, Milan, Italy
17Pharmacology and Toxicology, University of Oulu, Oulu, Finland
18Pharmacology, University of Arizona, Tucson, AZ, USA
19Biochemistry & Molecular Biology, University of Minnesota Medical School, Duluth, MN, USA
20The Japanese Society for the Study of Xenobiotics, Showa Pharmaceutical University, Machida, Tokyo, Japan
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.3 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2019102534718
Language: English
Published: Elsevier, 2018
Publish Date: 2019-10-25
Description:

Abstract

Several recent and prominent articles in Science and Nature deliberately mischaracterized the nature of genuine scientific evidence. Those articles take issue with the United States Environmental Protection Agency’s recent proposal to structure its policies and rules only from studies with transparently published raw data. The articles claim it is an effort to obfuscate with transparency, by eliminating a host of studies not offering raw data. A remarkable declaration by a Science editorial is that properly trained experts can verify the scientific evidence of studies without access to raw data, We assert the Agency’s proposal must be sustained. Transparency in reporting is a fundamental ethical imperative of objective scientific research justifying massive official regulations and policies. Putative hazards bereft of independent scientific evidence will continue to stoke public anxieties, calling for precautionary regulations and policies. These should rely not on spurious science but on transparent tradeoffs between the smallest exposures compatible with utility and with social perceptions of affordable precaution.

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Series: Regulatory toxicology and pharmacology
ISSN: 0273-2300
ISSN-E: 1096-0295
ISSN-L: 0273-2300
Volume: 97
Pages: A1 - A3
DOI: 10.1016/j.yrtph.2018.07.004
OADOI: https://oadoi.org/10.1016/j.yrtph.2018.07.004
Type of Publication: B1 Journal article
Field of Science: 317 Pharmacy
Subjects:
Copyright information: © 2018 Elsevier Inc. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/.
  https://creativecommons.org/licenses/by-nc-nd/4.0/