Growth after late-preterm birth and adult cognitive, academic, and mental health outcomes
Sammallahti, Sara; Heinonen, Kati; Andersson, Sture; Lahti, Marius; Pirkola, Sami; Lahti, Jari; Pesonen, Anu-Katriina; Lano, Aulikki; Wolke, Dieter; Eriksson, Johan G.; Kajantie, Eero; Raikkonen, Katri (2017-01-05)
Sammallahti, S., Heinonen, K., Andersson, S. et al. Growth after late-preterm birth and adult cognitive, academic, and mental health outcomes. Pediatr Res 81, 767–774 (2017) doi:10.1038/pr.2016.276
© 2017 International Pediatric Research Foundation, Inc. This is a post-peer-review, pre-copyedit version of an article published in Pediatric Research. The final authenticated version is available online at: https://doi.org/10.1038/pr.2016.276.
https://rightsstatements.org/vocab/InC/1.0/
https://urn.fi/URN:NBN:fi-fe2019111237658
Tiivistelmä
Abstract
Background: Late-preterm birth (at 340/7–366/7 wk gestation) increases the risk of early growth faltering, poorer neurocognitive functioning, and lower socio-economic attainment. Among early-preterm individuals, faster early growth benefits neurodevelopment, but it remains unknown whether these benefits extend to late-preterm individuals.
Methods: In 108 late-preterm individuals, we examined if weight, head, or length growth between birth, 5 and 20 months’ corrected age, and 56 mo, predicted grade point average and special education in comprehensive school, or neurocognitive abilities and psychiatric diagnoses/symptoms at 24–26 y of age.
Results: For every 1 SD faster weight and head growth from birth to 5 mo, and head growth from 5 to 20 mo, participants had 0.19–0.41 SD units higher IQ, executive functioning score, and grade point average (95% confidence intervals (CI) 0.002–0.59 SD), and lower odds of special education (odds ratio (OR) = 0.49–0.59, 95% CIs 0.28–0.97), after adjusting for sex, gestational age, follow-up age, and parental education. Faster head growth from 20 to 56 mo was associated with less internalizing problems; otherwise we found no consistent associations with mental health outcomes.
Conclusion: Faster growth during the critical early period after late-preterm birth is associated with better adult neurocognitive functioning, but not consistently with mental health outcomes.
Kokoelmat
- Avoin saatavuus [31995]