University of Oulu

Hulkkonen, S., Auvinen, J., Miettunen, J., Karppinen, J. and Ryhänen, J. (2019), Smoking as risk factor for carpal tunnel syndrome: A birth cohort study. Muscle Nerve, 60: 299-304. doi:10.1002/mus.26627

Smoking as risk factor for carpal tunnel syndrome : a birth cohort study

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Author: Hulkkonen, Sina1; Auvinen, Juha2; Miettunen, Jouko2;
Organizations: 1Department of Hand Surgery, Helsinki University Hospital and University of Helsinki, Finland, P.O. Box 266, FI-00029 HUS, Finland
2Center for Life Course Health Research, University of Oulu, Oulu, Finland
3Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.4 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2019111943040
Language: English
Published: John Wiley & Sons, 2019
Publish Date: 2020-07-06
Description:

Abstract

Background: Our aim was to determine whether maternal smoking and offspring’s own smoking affect the offspring’s risk for carpal tunnel syndrome (CTS).

Method: The study sample consisted of the Northern Finland Birth Cohort 1966 (N = 8703). Information on maternal smoking was collected from the participants’ mothers. At 31 years, information on smoking, body mass index, socioeconomic status, and long‐term illnesses were collected, combined with data of CTS diagnoses from the Care Register for Health Care (1997–2016).

Results: Maternal smoking was not associated with increased risk of CTS in offspring. Before the age of 31 years, smoking ≤10 pack years (hazard ratio [HR] = 1.54, 95% confidence interval [CI] = 1.11–2.15) and >10 pack years (HR = 1.90; 95% CI = 1.20–3.01) among women, and >10 pack years (HR = 1.89; 95% CI = 1.14–3.12) among men was associated with CTS compared with nonsmokers.

Conclusions: In this birth cohort, offsprings’ own smoking was associated with CTS; however, maternal smoking was not.

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Series: Muscle & nerve
ISSN: 0148-639X
ISSN-E: 1097-4598
ISSN-L: 0148-639X
Volume: 60
Issue: 3
Pages: 299 - 304
DOI: 10.1002/mus.26627
OADOI: https://oadoi.org/10.1002/mus.26627
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
3142 Public health care science, environmental and occupational health
Subjects:
Funding: The studies reported in this article were supportedby Vappu Uuspää foundation research grant for Sina Hulkkonen.
Copyright information: © 2019 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Hulkkonen, S. , Auvinen, J. , Miettunen, J. , Karppinen, J. and Ryhänen, J. (2019), Smoking as risk factor for carpal tunnel syndrome: A birth cohort study. Muscle Nerve, 60: 299-304. doi:10.1002/mus.26627, which has been published in final form at https://doi.org/10.1002/mus.26627. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.