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Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test |
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| Author: | Stavtsev, Dmitry D.1; Volkov, Mikhail V.2; Margaryants, Nikita B.2; |
| Organizations: |
1Research and Development Center of Biomedical Photonics, Orel State University named after I.S. Turgenev, 302020, Orel, Russia 2ITMO University, 197101, Saint-Petersburg, Russia 3OPEM, University of Oulu, 90014, Oulu, Finland |
| Format: | article |
| Version: | accepted version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 0.7 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe202001101706 |
| Language: | English |
| Published: |
SPIE,
2019
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| Publish Date: | 2020-01-10 |
| Description: |
AbstractVideocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases. see all
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| Series: |
Progress in biomedical optics and imaging |
| ISSN: | 1605-7422 |
| ISSN-E: | 2410-9045 |
| ISSN-L: | 1605-7422 |
| ISBN: | 978-1-5106-2821-2 |
| ISBN Print: | 978-1-5106-2820-5 |
| Pages: | 1 - 6 |
| Article number: | 11065 |
| DOI: | 10.1117/12.2523190 |
| OADOI: | https://oadoi.org/10.1117/12.2523190 |
| Host publication: |
Proceedings of SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, Saratov, Russian Federation, 24–28 September 2018 |
| Host publication editor: |
Genina, Elina A. Tuchin, Valery V. |
| Conference: |
International Symposium on Optics and Biophotonics |
| Type of Publication: |
A4 Article in conference proceedings |
| Field of Science: |
213 Electronic, automation and communications engineering, electronics 217 Medical engineering |
| Subjects: | |
| Funding: |
The research was supported by the grant of the RFBR-r_a (project 17-41-590560) in respect of the design and assembling of the experimental setup; by the grant of the President of the Russian Federation for state support of young Russian scientists № MK-3400.2018.8 in respect of conducting of the experiments; by Ministry of Science and Higher Education of the Russian Federation (Project No. 8.2501.2017/4.6) in respect of the design of the method and algorithm of VCS data processing and by the Russian Science Foundation (the research project 18-79-00237) in respect of LDF data processing and analysis, formulation of conclusions. |
| Copyright information: |
© (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only. Self-archived with the kind permission by the publisher. |