Ksenia Y. Kandurova, Viktor V. Dremin, Evgeny A. Zherebtsov, Elena V. Potapova, Mariya A. Filina, Andrey V. Dunaev, Andrian V. Mamoshin, Alexandr L. Alyanov, and Vadim F. Muradyan "Optical diagnostics of bile duct tissues state with tumor compression", Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 1106508 (3 June 2019); https://doi.org/10.1117/12.2522670
Optical diagnostics of bile duct tissues state with tumor compression
|Author:||Kandurova, Ksenia Y.1; Dremin, Viktor V.1; Zherebtsov, Evgeny A.1,2;|
1Research and Development Center of Biomedical Photonics, Orel State University named after I.S. Turgenev, Orel, Russia
2OPEM, University of Oulu, Oulu, Finland
3Orel Regional Clinical Hospital, Orel, Russia
|Online Access:||PDF Full Text (PDF, 0.5 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe202001101708
|Publish Date:|| 2020-01-10
The paper presents the results of in vivo experimental measurements of the endogenous fluorescence and blood perfusion in common bile duct tissues in obstructive jaundice patients during minimally invasive surgical operations. Nowadays the type of interventions become more widespread for treating hepatopancreatobiliary pathologies. An effective feedback which can be established by one or more optical diagnostic channels integrated into the standard instruments for minimally invasive manipulations would be of particular value to practical surgeons. To collect reference data, an experimental study has been conducted using a fiber optical probe with fluorescence spectroscopy and laser Doppler flowmetry channels. For every measurement, the areas of interest were different areas of common bile duct obstructed by a malignant tumor. Obtained results demonstrated significant variety registered intensities of fluorescence spectra and values of blood perfusion. Tested fiber optical endoscopic system showed sensitivity to the tissue state in the investigated area, so the two modal approach seems to be promising for further research and implementation in clinical practice.
Progress in biomedical optics and imaging
|Pages:||1 - 7|
Proceedings of SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, Saratov, Russian Federation, 24–28 September 2018
|Host publication editor:||
Genina, Elina A.
Tuchin, Valery V.
International Symposium on Optics and Biophotonics
|Type of Publication:||
A4 Article in conference proceedings
|Field of Science:||
217 Medical engineering
213 Electronic, automation and communications engineering, electronics
This study was supported by the Russian Science Foundation under project № 18-15-00201.
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