University of Oulu

Ksenia Y. Kandurova, Viktor V. Dremin, Evgeny A. Zherebtsov, Elena V. Potapova, Mariya A. Filina, Andrey V. Dunaev, Andrian V. Mamoshin, Alexandr L. Alyanov, and Vadim F. Muradyan "Optical diagnostics of bile duct tissues state with tumor compression", Proc. SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, 1106508 (3 June 2019);

Optical diagnostics of bile duct tissues state with tumor compression

Saved in:
Author: Kandurova, Ksenia Y.1; Dremin, Viktor V.1; Zherebtsov, Evgeny A.1,2;
Organizations: 1Research and Development Center of Biomedical Photonics, Orel State University named after I.S. Turgenev, Orel, Russia
2OPEM, University of Oulu, Oulu, Finland
3Orel Regional Clinical Hospital, Orel, Russia
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.5 MB)
Persistent link:
Language: English
Published: SPIE, 2019
Publish Date: 2020-01-10


The paper presents the results of in vivo experimental measurements of the endogenous fluorescence and blood perfusion in common bile duct tissues in obstructive jaundice patients during minimally invasive surgical operations. Nowadays the type of interventions become more widespread for treating hepatopancreatobiliary pathologies. An effective feedback which can be established by one or more optical diagnostic channels integrated into the standard instruments for minimally invasive manipulations would be of particular value to practical surgeons. To collect reference data, an experimental study has been conducted using a fiber optical probe with fluorescence spectroscopy and laser Doppler flowmetry channels. For every measurement, the areas of interest were different areas of common bile duct obstructed by a malignant tumor. Obtained results demonstrated significant variety registered intensities of fluorescence spectra and values of blood perfusion. Tested fiber optical endoscopic system showed sensitivity to the tissue state in the investigated area, so the two modal approach seems to be promising for further research and implementation in clinical practice.

see all

Series: Progress in biomedical optics and imaging
ISSN: 1605-7422
ISSN-E: 2410-9045
ISSN-L: 1605-7422
ISBN: 978-1-5106-2821-2
ISBN Print: 978-1-5106-2820-5
Pages: 1 - 7
DOI: 10.1117/12.2522670
Host publication: Proceedings of SPIE 11065, Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, Saratov, Russian Federation, 24–28 September 2018
Host publication editor: Genina, Elina A.
Tuchin, Valery V.
Conference: International Symposium on Optics and Biophotonics
Type of Publication: A4 Article in conference proceedings
Field of Science: 217 Medical engineering
213 Electronic, automation and communications engineering, electronics
Funding: This study was supported by the Russian Science Foundation under project № 18-15-00201.
Copyright information: © (2019) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only. Self-archived with the kind permission by the publisher.