Evgeny A. Zherebtsov, Elena V. Zharkikh, Igor O. Kozlov, Yulia I. Loktionova, Angelina I. Zherebtsova, Ilya E. Rafailov, Sergei G. Sokolovski, Victor V. Sidorov, Andrey V. Dunaev, and Edik U. Rafailov "Wearable sensor system for multipoint measurements of blood perfusion: pilot studies in patients with diabetes mellitus", Proc. SPIE 11079, Medical Laser Applications and Laser-Tissue Interactions IX, 110791O (22 July 2019); https://doi.org/10.1117/12.2526966
Wearable sensor system for multipoint measurements of blood perfusion : pilot studies in patients with diabetes mellitus
|Author:||Zherebtsov, Evgeny A.1,2; Zharkikh, Elena V.2; Kozlov, Igor O.2;|
1Optoelectronics and Measurement Techniques, University of Oulu, Oulu, FI-90014, Finland
2Research and Development Center of Biomedical Photonics, Orel State University named after I.S. Turgenev, Orel, Russia
3Aston Medical Technology Ltd., Birmingham, UK
4Aston Institute of Photonic Technologies, Aston University, Birmingham, UK
5SPE "LAZMA" Ltd, Moscow, Russia
|Online Access:||PDF Full Text (PDF, 0.5 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe202001101733
|Publish Date:|| 2020-01-10
The growing interest in the development of new wearable electronic devices for mobile healthcare provides great opportunities for the development of methods for assessing blood perfusion in this direction. Laser Doppler flowmetry (LDF) is one of the promising methods. A fine analysis of capillary blood ow structure and rhythm in the time and frequency domains, coupled with a new possibility of round-the-clock monitoring can provide valuable diagnostic information about the state of microvascular blood ow. In this study, wearable implementation of laser Doppler flowmetry was utilised for microcirculatory function assessment in patients with diabetes and healthy controls of two distinct age groups. Four wearable laser Doppler flowmetry monitors were used for the analysis of blood microcirculation. Thirty-seven healthy volunteers and 18 patients with type 2 diabetes mellitus participated in the study. The results of the studies have shown that the average perfusion differs between healthy volunteers of distinct age groups and between healthy volunteers of the younger age group and patients with diabetes mellitus. It was noted that the average level of perfusion measured on the wrist in the two groups of healthy volunteers has no statistically significant differences found in similar measurements on the fingertips. The wearable implementation of LDF can become a truly new diagnostic interface to monitor cardiovascular parameters, which could be of interest for diagnostics of conditions associated with microvascular disorders.
Proceedings of SPIE
Medical Laser Applications and Laser-Tissue Interactions IX 2019
|Host publication editor:||
Lilge, Lothar D.
Philipp, Carsten M.
Progress in Biomedical Optics and Imaging
|Type of Publication:||
A4 Article in conference proceedings
|Field of Science:||
213 Electronic, automation and communications engineering, electronics
217 Medical engineering
This study was funded by the Russian Science Foundation (the research project 18-79-00237). Evgeny Zherebtsov kindly acknowledges for personal support from grant of Academy of Finland No.318281 (data processing).
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