University of Oulu

Viktor Dremin, Evgeny Zherebtsov, Alexander Bykov, Alexey Popov, Alexander Doronin, and Igor Meglinski, "Influence of blood pulsation on diagnostic volume in pulse oximetry and photoplethysmography measurements," Appl. Opt. 58, 9398-9405 (2019)

Influence of blood pulsation on diagnostic volume in pulse oximetry and photoplethysmography measurements

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Author: Dremin, Viktor1,2; Zherebtsov, Evgeny1,2; Bykov, Alexander1;
Organizations: 1Opto-Electronics and Measurement Techniques Unit, Faculty of Information Technology and Electrical Engineering, University of Oulu, Oulu 90570, Finland
2Research & Development Center of Biomedical Photonics, Orel State University, Orel 302026, Russia
3Computer Graphics Group, School of Engineering and Computer Science, Victoria University ofWellington,Wellington 6140, New Zealand
4Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, Tomsk 634050, Russia
5Institute of Engineering Physics for Biomedicine (PhysBio), National Research Nuclear University (MEPhI), Moscow 115409, Russia
6Aston Institute of Materials Research, School of Engineering & Applied Science, Aston University, Birmingham B4 7ET, UK
7School of Life & Health Sciences, Aston University, Birmingham B4 7ET, UK
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 2.1 MB)
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Language: English
Published: Optical Society, 2019
Publish Date: 2020-03-03


Recent advances in the development of ultra-compact semiconductor lasers and technology of printed flexible hybrid electronics have opened broad perspectives for the design of new pulse oximetry and photoplethysmography devices. Conceptual design of optical diagnostic devices requires careful selection of various technical parameters, including spectral range; polarization and intensity of incident light; actual size, geometry, and sensitivity of the detector; and mutual position of the source and detector on the surface of skin. In the current study utilizing a unified Monte Carlo computational tool, we explore the variations in diagnostic volume due to arterial blood pulsation for typical transmitted and back-scattered probing configurations in a human finger. The results of computational studies show that the variations in diagnostic volumes due to arterial pulse wave are notably (up to 45%) different in visible and near-infrared spectral ranges in both transmitted and back-scattered probing geometries. While these variations are acceptable for relative measurements in pulse oximetry and/or photoplethysmography, for absolute measurements, an alignment normalization of diagnostic volume is required and can be done by a computational approach utilized in the framework of the current study.

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Series: Applied optics
ISSN: 1559-128X
ISSN-E: 2155-3165
ISSN-L: 1559-128X
Volume: 58
Issue: 34
Pages: 9398 - 9405
DOI: 10.1364/AO.58.009398
Type of Publication: A1 Journal article – refereed
Field of Science: 3141 Health care science
114 Physical sciences
217 Medical engineering
Funding: Academy of Finland (290596, 314369, 318281); Russian Science Foundation (19-79-00082); Russian Foundation for Basic Research (18-02-00669); MEPhI Academic Excellence Project (02.a03.21.0005); National Research Tomsk State University Academic D.I. Mendeleev Fund Program; Grant of the President of the Russian Federation for state support of young Russian scientists (MK-3400.2018.8); INFOTECH Oulu; Victoria University of Wellington (220732); Engineering and Physical Sciences Research Council, (EP/R024898/1).
Academy of Finland Grant Number: 290596
Detailed Information: 290596 (Academy of Finland Funding decision)
314369 (Academy of Finland Funding decision)
318281 (Academy of Finland Funding decision)
Copyright information: © 2019 Optical Society of America. sers may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.