University of Oulu

Kesäniemi, J.; Lavrinienko, A.; Tukalenko, E.; Mappes, T.; Watts, P.C.; Jurvansuu, J. Infection Load and Prevalence of Novel Viruses Identified from the Bank Vole Do Not Associate with Exposure to Environmental Radioactivity. Viruses 2020, 12, 44.

Infection load and prevalence of novel viruses identified from the bank vole do not associate with exposure to environmental radioactivity

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Author: Kesäniemi, Jenni1; Lavrinienko, Anton2; Tukalenko, Eugene3;
Organizations: 1Finland Ecology and Genetics Research Unit, University of Oulu, 90014 Oulu, Finland
2Department of Biological and Environmental Science, University of Jyväskylä, 40014 Jyväskylä, Finland
3National Research Center for Radiation Medicine of the National Academy of Medical Science, 02000 Kyiv, Ukraine
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.6 MB)
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Language: English
Published: Multidisciplinary Digital Publishing Institute, 2019
Publish Date: 2020-03-25


Bank voles (Myodes glareolus) are host to many zoonotic viruses. As bank voles inhabiting areas contaminated by radionuclides show signs of immunosuppression, resistance to apoptosis, and elevated DNA repair activity, we predicted an association between virome composition and exposure to radionuclides. To test this hypothesis, we studied the bank vole virome in samples of plasma derived from animals inhabiting areas of Ukraine (contaminated areas surrounding the former nuclear power plant at Chernobyl, and uncontaminated areas close to Kyiv) that differed in level of environmental radiation contamination. We discovered four strains of hepacivirus and four new virus sequences: two adeno-associated viruses, an arterivirus, and a mosavirus. However, viral prevalence and viral load, and the ability to cause a systemic infection, was not dependent on the level of environmental radiation.

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Series: Viruses
ISSN: 1999-4915
ISSN-E: 1999-4915
ISSN-L: 1999-4915
Volume: 12
Issue: 1
Article number: 44
DOI: 10.3390/v12010044
Type of Publication: A1 Journal article – refereed
Field of Science: 1181 Ecology, evolutionary biology
Funding: This research was funded by Kone foundation grant to J.J. and by the Finnish Academy to PCW (287153, 324602) and TM (268670, 324605).
Academy of Finland Grant Number: 268670
Detailed Information: 268670 (Academy of Finland Funding decision)
287153 (Academy of Finland Funding decision)
Copyright information: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (