University of Oulu

Jouko Miettunen, Marianne Haapea, Lassi Björnholm, Sanna Huhtaniska, Teija Juola, Lotta Kinnunen, Heli Lehtiniemi, Johannes Lieslehto, Nina Rautio & Tanja Nordström (2019) Psychiatric research in the Northern Finland Birth Cohort 1986 – a systematic review, International Journal of Circumpolar Health, 78:1, DOI: 10.1080/22423982.2019.1571382

Psychiatric research in the Northern Finland Birth Cohort 1986 : a systematic review

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Author: Miettunen, Jouko1,2; Haapea, Marianne1,2,3; Björnholm, Lassi3,4;
Organizations: 1Center for Life Course of Health Research, University of Oulu, Oulu, Finland
2Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
3Department of Psychiatry, Oulu University Hospital, Oulu, Finland
4Department of Psychiatry, Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland
5Northern Finland Birth Cohorts, Faculty of Medicine, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 2.5 MB)
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Language: English
Published: Informa, 2019
Publish Date: 2020-04-09


The Northern Finland Birth Cohort 1986 is a large population-based birth cohort, which aims to promote health and wellbeing of the population. In this paper, we systematically review the psychiatric research performed in the cohort until today, i.e. at the age of 32 years of the cohort (2018). We conducted a systematic literature search using the databases of PubMed and Scopus and complemented it with a manual search. We found a total of 94 articles, which were classified as examining ADHD, emotional and behavioural problems, psychosis risk or other studies relating to psychiatric subjects. The articles are mainly based on two large comprehensive follow-up studies of the cohort and several substudies. The studies have often used also nationwide register data. The studies have found several early predictors for the aforementioned psychiatric outcomes, such as problems at pregnancy and birth, family factors in childhood, physical inactivity and substance use in adolescence. There are also novel findings relating to brain imaging and cognition, for instance regarding familial risk of psychosis in relation to resting state functional MRI. The Northern Finland Birth Cohort 1986 has been utilised frequently in psychiatric research and future data collections are likely to lead to new scientifically important findings.

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Series: International journal of circumpolar health
ISSN: 1239-9736
ISSN-E: 2242-3982
ISSN-L: 1239-9736
Volume: 78
Issue: 1
Article number: 1571382
DOI: 10.1080/22423982.2019.1571382
Type of Publication: A2 Review article in a scientific journal
Field of Science: 3124 Neurology and psychiatry
Funding: This work was supported by the Academy of Finland [268336]; Alfred Kordelinin Säätiö; Juho Vainion Säätiö [201610329]; Orion Research foundation; Suomen Kulttuurirahasto [00160427]; Suomen Lääketieteen Säätiö.
Academy of Finland Grant Number: 268336
Detailed Information: 268336 (Academy of Finland Funding decision)
Copyright information: © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.