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Ultrafast diffusion exchange nuclear magnetic resonance |
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| Author: | Mankinen, Otto1; Zhivonitko, Vladimir V.1; Selent, Anne1; |
| Organizations: |
1NMR Research Unit, University of Oulu, P.O.Box 3000, FIN-90014 Oulu, Finland 2NANOMO Research Unit, University of Oulu, P.O. Box 3000, FIN-90014, Oulu, Finland |
| Format: | article |
| Version: | published version |
| Access: | open |
| Online Access: | PDF Full Text (PDF, 1.3 MB) |
| Persistent link: | http://urn.fi/urn:nbn:fi-fe2020063046413 |
| Language: | English |
| Published: |
Springer Nature,
2020
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| Publish Date: | 2020-06-30 |
| Description: |
AbstractThe exchange of molecules between different physical or chemical environments due to diffusion or chemical transformations has a crucial role in a plethora of fundamental processes such as breathing, protein folding, chemical reactions and catalysis. Here, we introduce a method for a single-scan, ultrafast NMR analysis of molecular exchange based on the diffusion coefficient contrast. The method shortens the experiment time by one to four orders of magnitude. Consequently, it opens the way for high sensitivity quantification of important transient physical and chemical exchange processes such as in cellular metabolism. As a proof of principle, we demonstrate that the method reveals the structure of aggregates formed by surfactants relevant to aerosol research. see all
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| Series: |
Nature communications |
| ISSN: | 2041-1723 |
| ISSN-E: | 2041-1723 |
| ISSN-L: | 2041-1723 |
| Volume: | 11 |
| Article number: | 3251 |
| DOI: | 10.1038/s41467-020-17079-7 |
| OADOI: | https://oadoi.org/10.1038/s41467-020-17079-7 |
| Type of Publication: |
A1 Journal article – refereed |
| Field of Science: |
114 Physical sciences 116 Chemical sciences |
| Subjects: | |
| Funding: |
The authors gratefully acknowledge funding from the European Research Council under Horizon 2020, projects Ultrafast Laplace NMR (grant agreement no. 772110) and SURFACE (grant agreement no. 717022), Academy of Finland (grant nos. 289649, 294027, 308238, 314175, 319216, 321701 and 323480), KAUTE foundation, Finnish Cultural Foundation–Fanny and Yrjö Similä fund, Tauno Tönning Foundation, Orion research foundation, Fortum Foundation and The University of Oulu Scholarship Foundation–Science Fund. The financial support from the Kvantum institute (University of Oulu) is also acknowledged. |
| EU Grant Number: |
(772110) UFLNMR - Ultrafast Laplace NMR (717022) SURFACE - The unexplored world of aerosol surfaces and their impacts. |
| Academy of Finland Grant Number: |
289649 294027 308238 314175 319216 321701 323480 |
| Detailed Information: |
289649 (Academy of Finland Funding decision) 294027 (Academy of Finland Funding decision) 308238 (Academy of Finland Funding decision) 314175 (Academy of Finland Funding decision) 319216 (Academy of Finland Funding decision) 321701 (Academy of Finland Funding decision) 323480 (Academy of Finland Funding decision) |
| Copyright information: |
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
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https://creativecommons.org/licenses/by/4.0/ |