University of Oulu

Hong, S.; Yuan, Y.; Zhang, K.; Lian, H.; Liimatainen, H. Efficient Hydrolysis of Chitin in a Deep Eutectic Solvent Synergism for Production of Chitin Nanocrystals. Nanomaterials 2020, 10, 869.

Efficient hydrolysis of chitin in a deep eutectic solvent synergism for production of chitin nanocrystals

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Author: Hong, Shu1,2; Yuan, Yang2; Zhang, Kaitao2;
Organizations: 1College of Materials Science and Engineering, Nanjing Forestry University, Nanjing 210037, China
2Fibre and Particle Engineering Research Unit, University of Oulu, P.O. Box 4300, 90014 Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 3.1 MB)
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Language: English
Published: Multidisciplinary Digital Publishing Institute, 2020
Publish Date: 2020-07-08


A deep eutectic solvent (DES) derived from ferric chloride hexahydrate and betaine chloride (molar ratio of 1:1) was used as hydrolytic media for production of chitin nanocrystals (ChNCs) with a high yield (up to 88.5%). The synergistic effect of Lewis acid and released Brønsted acid from betaine hydrochloride enabled the efficient hydrolysis of chitin for production of ChNCs coupled with ultrasonication with low energy consumption. The obtained ChNCs were with an average diameter of 10 nm and length of 268 nm, and a crystallinity of 89.2% with optimal synthesis conditions (at 100 °C for 1 h with chitin-to-DES mass ratio of 1:20). The ChNCs were further investigated as efficient emulsion stabilizers, and they resulted in stable o/w emulsions even at a high oil content of 50% with a low ChNC dosage of 1 mg/g. Therefore, a potential approach based on a DES on the production of chitin-based nanoparticles as emulsifiers is introduced.

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Series: Nanomaterials
ISSN: 2079-4991
ISSN-E: 2079-4991
ISSN-L: 2079-4991
Volume: 10
Issue: 5
Article number: 869
DOI: 10.3390/nano10050869
Type of Publication: A1 Journal article – refereed
Field of Science: 216 Materials engineering
Funding: This research was supported by grants from the National Natural Science Foundation of China (No. 31370567), Doctorate Fellowship Foundation of Nanjing Forestry University, National First-Class Disciplines, Priority Academic Program Development of Jiangsu Higher Education Institutions, and Academy of Finland project “Bionanochemicals” (No. 298295).
Academy of Finland Grant Number: 298295
Detailed Information: 298295 (Academy of Finland Funding decision)
Copyright information: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (