University of Oulu

Urbańczyk, M., Kharbanda, Y., Mankinen, O., Telkki, V. (2020) Accelerating Restricted Diffusion NMR Studies with Time-Resolved and Ultrafast Methods. Analytical Chemistry, 92 (14), 9948-9955.

Accelerating restricted diffusion NMR studies with time-resolved and ultrafast methods

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Author: Urbańczyk, Mateusz1; Kharbanda, Yashu1; Mankinen, Otto1,2;
Organizations: 1NMR Research Unit, University of Oulu, 90014 Oulu, Finland
2Oulu Functional NeuroImaging Group, Research Unit of Medical Imaging, Physics and Technology, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, 90029 Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.5 MB)
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Language: English
Published: American Chemical Society, 2020
Publish Date: 2020-08-25


Restricted diffusion of fluids in porous materials can be studied by pulsed field gradient nuclear magnetic resonance (NMR) non-invasively and without tracers. If the experiment is repeated many times with varying diffusion delays, detailed information about pore sizes and tortuosity can be recorded. However, the measurements are very time-consuming because numerous repetitions are needed for gradient ramping and varying diffusion delays. In this paper, we demonstrate two different strategies for acceleration of the restricted diffusion NMR measurements: time-resolved diffusion NMR and ultrafast Laplace NMR. The former is based on time-resolved non-uniform sampling, while the latter relies on spatial encoding of two-dimensional data. Both techniques allow similar 1–2 order of magnitude acceleration of acquisition, but they have different strengths and weaknesses, which we discuss in detail. The feasibility of the methods was proven by investigating restricted diffusion of water inside tracheid cells of thermally modified pine wood.

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Series: Analytical chemistry
ISSN: 0003-2700
ISSN-E: 1520-6882
ISSN-L: 0003-2700
Volume: 92
Issue: 14
Pages: 9948 - 9955
DOI: 10.1021/acs.analchem.0c01523
Type of Publication: A1 Journal article – refereed
Field of Science: 114 Physical sciences
116 Chemical sciences
Funding: The authors acknowledge the financial support of the European Research Council (ERC) under Horizon 2020 (H2020/2018-2022/ERC Grant Agreement 772110), the Academy of Finland (Grants 289649, 294027, and 319216), the Kvantum institute (University of Oulu), the CA15209 COST Action (EURELAX), the Finnish Cultural Foundation (Fanny and Yrjö Similä fund), the Fortum Foundation, and The University of Oulu Scholarship Foundation (Science Fund).
EU Grant Number: (772110) UFLNMR - Ultrafast Laplace NMR
Academy of Finland Grant Number: 289649
Detailed Information: 289649 (Academy of Finland Funding decision)
294027 (Academy of Finland Funding decision)
319216 (Academy of Finland Funding decision)
Copyright information: © 2020 American Chemical Society. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.