University of Oulu

Siiskonen, M., Hirn, I., Pesälä, R., Hautala, T., Ohtonen, P. and Hautala, N. (2021), Prevalence, incidence and epidemiology of childhood uveitis. Acta Ophthalmol, 99: e160-e163.

Prevalence, incidence and epidemiology of childhood uveitis

Saved in:
Author: Siiskonen, Mira1,2,3,4; Hirn, Iida2,3; Pesälä, Roosa2,3;
Organizations: 1Department of Ophthalmology, Oulu University Hospital, Oulu, Finland
2PEDEGO Research Unit, Oulu, Finland
3Medical Research Center, University of Oulu, Oulu, Finland
4Division of Operative Care, Oulu University Hospital, Oulu, Finland
5Research Unit of Biomedicine, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
Persistent link:
Language: English
Published: John Wiley & Sons, 2021
Publish Date: 2020-09-01


Purpose: To analyse the prevalence, incidence and aetiology of paediatric uveitis.

Methods: A retrospective, population‐based cohort study of Finnish children with uveitis in Northern Ostrobothnia Hospital District in 2008–2017. The data included parameters for age, gender, age at diagnosis, laterality, chronicity, anatomical distribution of the disease, aetiology and systemic association.

Results: One hundred fifty patients aged <16 years (mean age 6.9 ± 3.9 years) with uveitis were included, out of whom 53% were girls. The first uveitis episode occurred at 1–6 years in 59%, and 62% of them were girls. In the age group of 7–15 years, boys were diagnosed with uveitis more frequently than girls (61% versus 39%, respectively). Seventy percent of the girls were diagnosed with their first uveitis episode at the age of 1–6 years, whereas only 48% of the boys were diagnosed at that age. The prevalence of uveitis increased from 64/100 000 children <16 years in 2008 (95% CI, 47.7–84.2) to 106/100 000 in 2017 (95% CI, 84.6–130.2). The incidence of childhood uveitis in 2008–2017 was 14/100 000 person‐years in children <16 years (95% CI, 11.3–16.5). Eighty‐seven percent of the cases were non‐infectious, 9% were infectious, and 3% had masquerade syndromes. Sixty‐one percent of patients had juvenile idiopathic arthritis (JIA).

Conclusion: The prevalence of paediatric uveitis has increased during the last decade in both genders. Uveitis is more frequent in girls, and they were diagnosed at a younger age than boys. Idiopathic cases and JIA accounted for a majority of aetiological features.

see all

Series: Acta ophthalmologica
ISSN: 1755-375X
ISSN-E: 1755-3776
ISSN-L: 1755-375X
Volume: 99
Issue: 2
Pages: e160 - e163
DOI: 10.1111/aos.14535
Type of Publication: A1 Journal article – refereed
Field of Science: 3125 Otorhinolaryngology, ophthalmology
Funding: The present study was supported by the grants from Eye Foundation, Eye and Tissue Bank Foundation, Mary and Georg C. Ehrnrooths Foundation and Finnish Ophthalmological Society.
Copyright information: © 2020 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.