University of Oulu

Jyväkorpi, S.K., Urtamo, A., Kivimäki, M. et al. Associations of protein source, distribution and healthy dietary pattern with appendicular lean mass in oldest-old men: the Helsinki Businessmen Study (HBS). Eur Geriatr Med 11, 699–704 (2020).

Associations of protein source, distribution and healthy dietary pattern with appendicular lean mass in oldest-old men : the Helsinki Businessmen Study (HBS)

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Author: Jyväkorpi, S. K.1; Urtamo, A.1; Kivimäki, M.1;
Organizations: 1University of Helsinki, Clinicum and Helsinki University Central Hospital, Unit of Primary Health Care, Tukholmankatu 8 B, 00014, Helsinki, Finland
2University of Helsinki, Clinicum, and Helsinki University Hospital, Helsinki, Finland
3University of Oulu, Center for Life Course Health Research, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.4 MB)
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Language: English
Published: John Wiley & Sons, 2020
Publish Date: 2020-11-10


Purpose: We explored how food and dietary intakes, protein daily distribution and source are associated with appendicular lean mass (ALM)/m² of the oldest-old community-dwelling men.

Methods: Cross-sectional analyses of Helsinki Businessmen Study (HBS, mean age 87 years) participants who came to clinic visit in 2017/2018. Nutritional status, physical performance and fasting blood samples were measured. Food and dietary intakes were retrieved from 3-day food diaries. Body composition was measured and appendicular lean mass (ALM) per m² was dichotomized as ALM/m² < 7 kg/m² and ≥ 7 kg/m². Differences between lower and higher ALM were analyzed using t test or Mann–Whitney U test. Analysis of covariance was used to investigate independent associations with ALM/m².

Results: Random sample of 130 participants took part in the medical examinations, 126 returned food diaries, and 102 underwent DXA-scan. ALM/m² was associated with total protein (p = 0.033), animal protein (p = 0.043) and meat protein (p = 0.033) intakes. Protein distribution between daily meals differed at lunch; those with higher ALM/m² ate more protein (p = 0.047) at lunch. Consumption of fruits, vegetables (p = 0.022) and meat (p = 0.006) was associated with ALM/m².

Conclusion: Protein intake, source and distribution as well fruit and vegetable intakes were associated with higher ALM in oldest-old men.

Study registration: The study is registered with identifier: NCT02526082.

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Series: European geriatric medicine
ISSN: 1878-7649
ISSN-E: 1878-7657
ISSN-L: 1878-7649
Volume: 11
Issue: 4
Pages: 699 - 704
DOI: 10.1007/s41999-020-00330-1
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
3141 Health care science
Funding: This work was supported by Foundation of Nutrition Research, VTR-funding of the Helsinki University Hospital (EVO), Helsinki University Hospital Internal Medicine and Rehabilitation and Academy of Finland, grant number 311492, NordForsk, and Helsinki Institute of Life Science. The sponsors did not have any role in the study design, analysis or interpretation of data, or in writing the report or the decision to submit this article. The authors were independent researchers not associated with the funders.
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