University of Oulu

Elena V. Zharkikh, Yulia I. Loktionova, Igor O. Kozlov, Angelina I. Zherebtsova, Victor V. Sidorov, Evgeny A. Zherebtsov, Andrey V. Dunaev, and Edik U. Rafailov "Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus", Proc. SPIE 11363, Tissue Optics and Photonics, 113631K (2 April 2020); https://doi.org/10.1117/12.2552464

Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus

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Author: Zharkikh, Elena V.1; Loktionova, Yulia I.1; Kozlov, Igor O.1;
Organizations: 1Research Development Center of Biomedical Photonics, Orel State University named after I.S. Turgenev, 95 Komsomolskaya St, Orel, 302026, Russia
2Opto-Electronics and Measurement Techniques Research Unit, University of Oulu, Oulu, 90570, Finland
3Aston Institute of Photonic Technologies, Aston University, Aston Triangle, Birmingham, B4 7ET, UK
Format: abstract
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 2.6 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2020111189952
Language: English
Published: Society of Photo-Optical Instrumentation Engineers (SPIE), 2020
Publish Date: 2020-11-11
Description:

Abstract

The article is aimed at conducting pilot studies of microcirculation changes in patients with diabetes mellitus during the course of intravenous infusions of alpha lipoic acid. The study was conducted with patients with diabetes during the passage of a standard course of treatment. The change in parameters was compared before the start of the infusion course, during and after the course. A system of wearable laser Doppler monitors was used to conduct the study. The study showed that although the microcirculation index does not undergo significant changes during the treatment process, spectral analysis of the recorded signal has potential applicability. Further studies with a larger sample group are required for a qualitative analysis of the observed effects.

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Article number: 113631K
DOI: 10.1117/12.2552464
OADOI: https://oadoi.org/10.1117/12.2552464
Host publication: Proceedings Volume 11363, Tissue Optics and Photonics
Host publication editor: Tuchin, Valery V.
Blondel, Walter C. P. M.
Zalevsky, Zeev
Conference: Spie Photonics Europe
Field of Science: 217 Medical engineering
Subjects:
Funding: This study was funded by the Russian Science Foundation (the research project 18-79-00237).
Copyright information: © (2020) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.