Balogun, H.A.; Rantala, A.K.; Antikainen, H.; Siddika, N.; Amegah, A.K.; Ryti, N.R.I.; Kukkonen, J.; Sofiev, M.; Jaakkola, M.S.; Jaakkola, J.J.K. Effects of Air Pollution on the Risk of Low Birth Weight in a Cold Climate. Appl. Sci. 2020, 10, 6399. https://doi.org/10.3390/app10186399
Effects of air pollution on the risk of low birth weight in a cold climate
|Author:||Balogun, Hamudat A.1,2,3; Rantala, Aino K.1,2,3; Antikainen, Harri4;|
1Center for Environmental and Respiratory Health Research, Faculty of Medicine, University of Oulu, FI-90014 Oulu, Finland
2Medical Research Center Oulu, University of Oulu and Oulu University Hospital, FI-90014 Oulu, Finland
3Biocenter Oulu, University of Oulu, FI-90014 Oulu, Finland
4Geography Research Unit, University of Oulu, 90014 Oulu, Finland
5Public Health Research Group, Department of Biomedical Sciences, University of Cape Coast, Cape Coast, Ghana
6Finnish Meteorological Institute, FI-00101 Helsinki, Finland
|Online Access:||PDF Full Text (PDF, 0.3 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2020111690422
Multidisciplinary Digital Publishing Institute,
|Publish Date:|| 2020-11-16
There is accumulating evidence that prenatal exposure to air pollution disturbs fetal growth and development, but little is known about these effects in cold climates or their season-specific or joint effects. Our objective was to assess independent and joint effects of prenatal exposure to specific air pollutants on the risk of low birth weight (LBW). We utilized the 2568 children of the Espoo Cohort Study, born between 1984 and 1990 and living in the City of Espoo. We conducted stratified analyses for births during warm and cold seasons separately. We analyzed the effect estimates using multi-pollutant Poisson regression models with risk ratio (RR) as the measure of effect. The risk of LBW was related to exposure to CO (adjusted RR 1.44, 95% confidence interval [CI]: 1.04–2.00) and exposure to O₃ in the spring–summer season (1.82, 1.11–2.96). There was also evidence of synergistic effects between CO and O₃ (relative risk due to interaction (RERI), all year 1.08, 95% CI: 0.27–4.94, spring–summer 3.97, 2.17–25.85) and between PM2.5 and O₃ (all year 0.72, −0.07–3.60, spring–summer 2.80, 1.36–19.88). We present new evidence of both independent and joint effects of prenatal exposure to low levels of air pollution in a cold climate on the risk of LBW.
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3142 Public health care science, environmental and occupational health
This study was supported by the Academy of Finland (grant numbers 266314, 267675, 267995 (APTA Consortium), 310372, and 313073 (GLORIA Consortium)) and by The Research Foundation of the Pulmonary Diseases. N.S. received PhD scholarships from the Health and Biosciences Doctoral Programme (HBS-DP), University of Oulu and the University of Oulu Scholarship Foundation.
|Academy of Finland Grant Number:||
266314 (Academy of Finland Funding decision)
267995 (Academy of Finland Funding decision)
310372 (Academy of Finland Funding decision)
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).