University of Oulu

Zharkikh, E, Dremin, V, Zherebtsov, E, Dunaev, A, Meglinski, I. Biophotonics methods for functional monitoring of complications of diabetes mellitus. J. Biophotonics. 2020; 13:e202000203.

Biophotonics methods for functional monitoring of complications of diabetes mellitus

Saved in:
Author: Zharkikh, Elena1; Dremin, Viktor1,2; Zherebtsov, Evgeny1,3;
Organizations: 1Research & Development Center of Biomedical Photonics, Orel State University, Orel, Russia
2School of Engineering and Applied Science, Aston University, Birmingham, UK
3Optoelectronics and Measurement Techniques unit, University of Oulu, Oulu, Finland
4Interdisciplinary Laboratory of Biophotonics, National Research Tomsk State University, Tomsk, Russia
5Institute of Engineering Physics for Biomedicine (PhysBio), National Research Nuclear University—MEPhI, Moscow, Russia
6School of Life and Health Sciences, Aston University, Birmingham, UK
7Department of Histology, Cytology and Embryology, Institute of Clinical Medicine N.V. Sklifosovsky, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 8 MB)
Persistent link:
Language: English
Published: John Wiley & Sons, 2020
Publish Date: 2020-12-03


The prevalence of diabetes complications is a significant public health problem with a considerable economic cost. Thus, the timely diagnosis of complications and prevention of their development will contribute to increasing the length and quality of patient life, and reducing the economic costs of their treatment. This article aims to review the current state‐of‐the‐art biophotonics technologies used to identify the complications of diabetes mellitus and assess the quality of their treatment. Additionally, these technologies assess the structural and functional properties of biological tissues, and they include capillaroscopy, laser Doppler flowmetry and hyperspectral imaging, laser speckle contrast imaging, diffuse reflectance spectroscopy and imaging, fluorescence spectroscopy and imaging, optical coherence tomography, optoacoustic imaging and confocal microscopy. Recent advances in the field of optical noninvasive diagnosis suggest a wider introduction of biophotonics technologies into clinical practice and, in particular, in diabetes care units.

see all

Series: Journal of biophotonics
ISSN: 1864-063X
ISSN-E: 1864-0648
ISSN-L: 1864-063X
Volume: 13
Issue: 10
Article number: e202000203
DOI: 10.1002/jbio.202000203
Type of Publication: A1 Journal article – refereed
Field of Science: 217 Medical engineering
3121 General medicine, internal medicine and other clinical medicine
Funding: VD acknowledges personal support from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska‐Curie grant agreement No. 839888. EZ acknowledges personal support from the Academy of Finland (grant 318281). IM acknowledge partial support from MEPhI Academic Excellence Project (Contract No. 02.a03.21.0005) and the National Research Tomsk State University Academic D.I. Mendeleev Fund Program. Authors also acknowledge the support of the Academy of Finland (grants 326204, 325097).
Academy of Finland Grant Number: 318281
Detailed Information: 318281 (Academy of Finland Funding decision)
326204 (Academy of Finland Funding decision)
325097 (Academy of Finland Funding decision)
Copyright information: © 2020 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited