University of Oulu

Kallio, M, Rahtu, M, van Kaam, AH, Bayford, R, Rimensberger, PC, Frerichs, I. Electrical impedance tomography reveals pathophysiology of neonatal pneumothorax during NAVA. Clin Case Rep. 2020; 8: 1574– 1578.

Electrical impedance tomography reveals pathophysiology of neonatal pneumothorax during NAVA

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Author: Kallio, Merja1,2; Rahtu, Marika1,2; van Kaam, Anton H.3;
Organizations: 1PEDEGO Research Unit, University of Oulu, Oulu, Finland
2Department of Children and Adolescents, Oulu University Hospital, Oulu, Finland
3Department of Neonatology, Emma Children’s Hospital, Amsterdam UMC, University of Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
4Department of Natural Sciences, Middlesex University, London, UK
5Division of Neonatology and Pediatric Intensive Care, University Hospital of Geneva, University of Geneva, Geneva, Switzerland
6Department of Anesthesiology and Intensive Care Medicine, University Medical Centre Schleswig‐Holstein, Kiel, Germany
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.1 MB)
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Language: English
Published: John Wiley & Sons, 2020
Publish Date: 2020-12-04


Pneumothorax is a potentially life‐threatening complication of neonatal respiratory distress syndrome (RDS). We describe a case of a tension pneumothorax that occurred during neurally adjusted ventilatory assist (NAVA) in a preterm infant suffering from RDS. The infant was included in a multicenter study examining the role of electrical impedance tomography (EIT) in intensive care and therefore continuously monitored with this imaging method. The attending physicians were blinded for EIT findings but offline analysis revealed the potential of EIT to clarify the underlying cause of this complication, which in this case was heterogeneous lung disease resulting in uneven ventilation distribution. Instantaneous increase in end‐expiratory lung impedance on the affected side was observed at time of the air leak. Real‐time bedside availability of EIT data could have modified the treatment decisions made.

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Series: Clinical case reports
ISSN: 2050-0904
ISSN-E: 2050-0904
ISSN-L: 2050-0904
Volume: 8
Issue: 8
Pages: 1574 - 1578
DOI: 10.1002/ccr3.2944
Type of Publication: A1 Journal article – refereed
Field of Science: 3123 Gynaecology and paediatrics
Funding: The study was funded by the European Union's Horizon 2020 Research and Innovation Program (Project CRADL, grant agreement number 668259) and by the Swiss State Secretariat for education, research and Innovation (SERI) under contract number 15.0342‐1. Dr Kallio was supported by The Finnish Foundation for Pediatric Research. MD Rahtu received a personal research grant from The Alma and KA Snellman Foundation, Oulu, Finland.
Copyright information: © 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.