Ruszczyński, M, Ambrożej, D, Adamiec, A, et al. Preschool wheezing and asthma in children: A systematic review of guidelines and quality appraisal with the AGREE II instrument. Pediatr Allergy Immunol. 2021; 32: 92– 105. https://doi.org/10.1111/pai.13334
Preschool wheezing and asthma in children : a systematic review of guidelines and quality appraisal with the AGREE II instrument
|Author:||Ruszczyński, Marek1; Ambrożej, Dominika2; Adamiec, Aleksander2;|
1Department of Pediatrics, Medical University of Warsaw, Warsaw, Poland
2Warsaw Medical University, Warsaw, Poland
3Department of Pediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland
4Department of Pediatrics, Turku University Hospital and University of Turku, Turku, Finland
5Department of Pediatric Allergy and Immunology, Istanbul Medeniyet University Faculty of Medicine, Goztepe Training and Research Hospital, Istanbul, Turkey
6Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
7Imperial College Healthcare NHS Trust, London, United Kingdom
8Division of Infection, Immunity & Respiratory Medicine, University of Manchester, U.K.
9Astrid Lindgren Children’s Hospital Stockholm Sweden Karolinska University Hospital, Stockholm, Sweden
10Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden
11Pediatric Allergology, Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, German Center for Lung Research (DZL), LMU Munich, Munich, Germany,
12Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
13Department of Pediatrics, University of Oulu, Oulu, Finland
|Online Access:||PDF Full Text (PDF, 1.8 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe202102013403
John Wiley & Sons,
|Publish Date:|| 2021-08-20
Background: Asthma‐like symptoms in preschool children, such as wheezing and dyspnea, are common time‐ and resource‐consuming diagnostic and management challenges. Quality of wheezing and asthma recommendations varies. The purpose of this study, carried out by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force for Preschool Wheeze, was to systematically review and assess the quality of guidelines for diagnosis and treatment of preschool wheezing and/or asthma.
Methods: The Cochrane Library, MEDLINE, and EMBASE were searched until June 2018. The methodological rigor, quality, and transparency of relevant guidelines were assessed with the use of the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool.
Results: We identified 26 guidelines. The quality scores for each domain varied. Of all domains, clarity and presentation had the highest mean score, whereas applicability and stakeholder involvement had the lowest. The scores (median) for individual domains were as follows: score and purpose 86%; stakeholder involvement 49%; rigor of development 54%; clarity of presentation 85%; applicability 51%; and editorial independence 63%.
Conclusion: Although several guidelines on asthma management in children are available, however, their quality varies. Additionally, there is a considerable gap in reliable recommendations on the management and treatment of non‐asthmatic preschool wheeze.
Pediatric allergy and immunology
|Pages:||92 - 105|
|Type of Publication:||
A2 Review article in a scientific journal
|Field of Science:||
3121 General medicine, internal medicine and other clinical medicine
3123 Gynaecology and paediatrics
European Academy of Allergy and Clinical Immunology.
© 2020 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. This is the peer reviewed version of the following article: Ruszczyński, M, Ambrożej, D, Adamiec, A, et al. Preschool wheezing and asthma in children: A systematic review of guidelines and quality appraisal with the AGREE II instrument. Pediatr Allergy Immunol. 2021; 32: 92– 105, which has been published in final form at https://doi.org/10.1111/pai.13334. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.