Processing of pragmatic communication in ASD : a video-based brain imaging study |
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Author: | Kotila, Aija1; Hyvärinen, Aapo2; Mäkinen, Leena1; |
Organizations: |
1Research Unit of Logopedics, Faculty of Humanities, University of Oulu, Oulu, Finland 2Department of Computer Science, University of Helsinki, Helsinki, Finland 3Office of the Vice Chancellor, Murdoch University, Murdoch, WA, Australia
4Research Unit of Clinical Neuroscience, Psychiatry, University of Oulu, Oulu, Finland
5PEDEGO Research Unit, The Faculty of Medicine, University of Oulu, Oulu, Finland 6Department of Child Psychiatry, Faculty of Medicine, Institute of Clinical Medicine, Oulu University Hospital, Oulu, Finland 7Department of Diagnostic Radiology, Medical Research Center (MRC), University and University Hospital of Oulu, Oulu, Finland 8Research Unit of Medical Imaging, Physics and Technology, The Faculty of Medicine, University of Oulu, Oulu, Finland |
Format: | article |
Version: | published version |
Access: | open |
Online Access: | PDF Full Text (PDF, 3.9 MB) |
Persistent link: | http://urn.fi/urn:nbn:fi-fe202102023495 |
Language: | English |
Published: |
Springer Nature,
2020
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Publish Date: | 2021-02-02 |
Description: |
AbstractSocial and pragmatic difficulties in autism spectrum disorder (ASD) are widely recognized, although their underlying neural level processing is not well understood. The aim of this study was to examine the activity of the brain network components linked to social and pragmatic understanding in order to reveal whether complex socio-pragmatic events evoke differences in brain activity between the ASD and control groups. Nineteen young adults (mean age 23.6 years) with ASD and 19 controls (mean age 22.7 years) were recruited for the study. The stimulus data consisted of video clips showing complex social events that demanded processing of pragmatic communication. In the analysis, the functional magnetic resonance imaging signal responses of the selected brain network components linked to social and pragmatic information processing were compared. Although the processing of the young adults with ASD was similar to that of the control group during the majority of the social scenes, differences between the groups were found in the activity of the social brain network components when the participants were observing situations with concurrent verbal and non-verbal communication events. The results suggest that the ASD group had challenges in processing concurrent multimodal cues in complex pragmatic communication situations. see all
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Series: |
Scientific reports |
ISSN: | 2045-2322 |
ISSN-E: | 2045-2322 |
ISSN-L: | 2045-2322 |
Volume: | 10 |
Article number: | 21739 |
DOI: | 10.1038/s41598-020-78874-2 |
OADOI: | https://oadoi.org/10.1038/s41598-020-78874-2 |
Type of Publication: |
A1 Journal article – refereed |
Field of Science: |
616 Other humanities 3112 Neurosciences |
Subjects: | |
Funding: |
This study was supported by the Academy of Finland, the Alma and K. A. Snellman Foundation, Oulu, Finland and Eudaimonia Institute, University of Oulu. |
Copyright information: |
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
https://creativecommons.org/licenses/by/4.0/ |