University of Oulu

Kerkelä M, Gyllenberg D, Gissler M, et al. Cumulative incidences of hospital‐treated psychiatric disorders are increasing in five Finnish birth cohorts. Acta Psychiatr Scand. 2021;143:119–129.

Cumulative incidences of hospital‐treated psychiatric disorders are increasing in five Finnish birth cohorts

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Author: Kerkelä, Martta1; Gyllenberg, David2,3,4; Gissler, Mika2,3,5;
Organizations: 1Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland
2Deparment of Child Psychiatry, INVEST Research Flagship Center, Turku University Hospital, University of Turku, Turku, Finland
3Finnish Institute for Health and Welfare, Helsinki, Finland
4Department of Adolescent Psychiatry, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
5Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden
6PEDEGO Research Unit, Clinic of Child Psychiatry, University of Oulu, University Hospital of Oulu, Oulu, Finland
7Center for Life Course Health Research, University of Oulu, Oulu, Finland
8Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland
9Department of Psychiatry, University Hospital of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
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Language: English
Published: John Wiley & Sons, 2021
Publish Date: 2021-02-19


Objective: The aim of this study was to explore changes in the incidences of childhood and early adulthood hospital‐treated psychiatric disorders in five large Finnish birth cohorts of individuals born between 1966 and 1997.

Methods: The five birth cohorts were as follows: Northern Finland Birth Cohort 1966 (NFBC 1966) and 1986 (NFBC 1986), 1987 Finnish Birth Cohort (FBC 1987) and 1997 (FBC 1997), and Finnish 1981 Birth Cohort Study (FBCS 1981). Incidences of hospital‐treated psychiatric disorders in each cohort were calculated separately for males (N = 71,209) and females (N = 65,190). Poisson regression was used to test difference in proportions of psychiatric disorders in wide range of diagnosis classes separately in childhood and adolescence, and early adulthood.

Results: The total incidences of psychiatric disorders in childhood and adolescence among males has increased in the birth cohorts over decades (Incidence Rate Ratio, IRR = 1.04 (1.04–1.05); p < 0.001). Similar result was seen among females (IRR = 1.04 (1.03–1.04); p < 0.001). In early adulthood, there was significant increase among females (IRR = 1.04 (1.03–1.05);p < 0.001), but among males, the change was not significant (IRR = 0.99 (0.99–1.00), p = 0.051).

Conclusions: The main finding was that the cumulative incidence of hospital‐treated psychiatric disorders increased over the decades in Finland. The increasing trend in hospital‐treated psychiatric disorders in early adulthood was detected in females but not in males. In the youngest cohorts, the cumulative incidence of hospital‐treated psychiatric disorders was at the same level in males and females, whereas in oldest cohort, males had higher incidence than females.

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Series: Acta psychiatrica Scandinavica
ISSN: 0001-690X
ISSN-E: 1600-0447
ISSN-L: 0001-690X
Volume: 143
Issue: 2
Pages: 119 - 129
DOI: 10.1111/acps.13247
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
3124 Neurology and psychiatry
Funding: The Finnish Psychiatric Birth Cohort Consortium (PSYCOHORTS) received grant no. 308555 from the Academy of Finland. This research was supported by the INVEST Research Flagship, and this research was funded by the Academy of Finland Flagship Programme (decision number: 320162).
Academy of Finland Grant Number: 308555
Detailed Information: 308555 (Academy of Finland Funding decision)
Copyright information: © 2020 The Authors. Acta Psychiatrica Scandinavica published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.