University of Oulu

Prunskaite-Hyyryläinen R. (2019) Optical Projection Tomography Imaging to Study Kidney Organogenesis. In: Vainio S. (eds) Kidney Organogenesis. Methods in Molecular Biology, vol 1926. Humana Press, New York, NY.

Optical projection tomography imaging to study kidney organogenesis

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Author: Prunskaite-Hyyryläinen, Renata1
Organizations: 1Faculty of Biochemistry and Molecular Medicine, University of Oulu, Finland
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 4.9 MB)
Persistent link:
Language: English
Published: Humana Press, 2019
Publish Date: 2021-03-09


Optical projection tomography (OPT) is a 3D imaging technology. The 3D tomographic reconstruction permits precise analysis and quantification of various structures in developing embryonic tissues and adult organs of small rodents or biopsies. OPT enables detailed and accurate studies of kidney organogenesis, namely, ureteric tree branching morphogenesis and nephron quantification.

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Series: Methods in molecular biology
ISSN: 1064-3745
ISSN-E: 1940-6029
ISSN-L: 1064-3745
ISBN: 978-1-4939-9021-4
ISBN Print: 978-1-4939-9020-7
Volume: 1926
Pages: 185 - 199
DOI: 10.1007/978-1-4939-9021-4_16
Host publication: Kidney organogenesis : methods and protocols
Host publication editor: Vainio, Seppo
Type of Publication: A3 Book chapter
Field of Science: 1184 Genetics, developmental biology, physiology
Copyright information: © Springer Science+Business Media, LLC, part of Springer Nature 2019. This is a post-peer-review, pre-copyedit version of an article published in Methods in Molecular Biology. The final authenticated version is available online at