University of Oulu

Jandacka D, Uchytil J, Zahradnik D, Farana R, Vilimek D, Skypala J, Urbaczka J, Plesek J, Motyka A, Blaschova D, Beinhauerova G, Rygelova M, Brtva P, Balazova K, Horka V, Malus J, Silvernail JF, Irwin G, Nieminen MT, Casula V, Juras V, Golian M, Elavsky S, Knapova L, Sram R, Hamill J. Running and Physical Activity in an Air-Polluted Environment: The Biomechanical and Musculoskeletal Protocol for a Prospective Cohort Study 4HAIE (Healthy Aging in Industrial Environment—Program 4). International Journal of Environmental Research and Public Health. 2020; 17(23):9142.

Running and physical activity in an air-polluted environment : the biomechanical and musculoskeletal protocol for a prospective cohort study 4HAIE (Healthy Aging in Industrial Environment—Program 4)

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Author: Jandacka, Daniel1; Uchytil, Jaroslav1; Zahradnik, David1;
Organizations: 1Univ Ostrava, Human Mot Diagnost Ctr, Dept Human Movement Studies, Ostrava 70200, Czech Republic.
2Univ Nevada, Dept Kinesiol & Nutr Sci, Las Vegas, NV 89154 USA.
3Cardiff Metropolitan Univ, Cardiff Sch Sport & Hlth Sci, Cardiff CF5 2YB, Wales.
4Univ Oulu, Res Unit Med Imaging Phys & Technol, FI-90014 Oulu, Finland.
5Med Univ Vienna, High Field MR Ctr, Dept Biomed Imaging & Image Guided Therapy, A-1090 Vienna, Austria.
6Inst Expt Med AS CR, Prague 14220, Czech Republic.
7Univ Massachusetts, Dept Kinesiol, Amherst, MA 01003 USA.
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 3.2 MB)
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Language: English
Published: Multidisciplinary Digital Publishing Institute, 2020
Publish Date: 2021-03-10


Far too little attention has been paid to health effects of air pollution and physical (in)activity on musculoskeletal health. The purpose of the Healthy aging in industrial environment study (4HAIE) is to investigate the potential impact of physical activity in highly polluted air on musculoskeletal health. A total of 1500 active runners and inactive controls aged 18–65 will be recruited. The sample will be recruited using quota sampling based on location (the most air-polluted region in EU and a control region), age, sex, and activity status. Participants will complete online questionnaires and undergo a two-day baseline laboratory assessment, including biomechanical, physiological, psychological testing, and magnetic resonance imaging. Throughout one-year, physical activity data will be collected through Fitbit monitors, along with data regarding the incidence of injuries, air pollution, psychological factors, and behavior collected through a custom developed mobile application. Herein, we introduce a biomechanical and musculoskeletal protocol to investigate musculoskeletal and neuro-mechanical health in this 4HAIE cohort, including a design for controlling for physiological and psychological injury factors. In the current ongoing project, we hypothesize that there will be interactions of environmental, biomechanical, physiological, and psychosocial variables and that these interactions will cause musculoskeletal diseases/protection.

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Series: International journal of environmental research and public health
ISSN: 1661-7827
ISSN-E: 1660-4601
ISSN-L: 1661-7827
Volume: 17
Issue: 23
Article number: 9142
DOI: 10.3390/ijerph17239142
Type of Publication: A1 Journal article – refereed
Field of Science: 3142 Public health care science, environmental and occupational health
Funding: This research was co-funded by European union and Ministry of Education, Youth and Sports of the Czech Republic, grant number CZ.02.1.01/0.0/0.0/16_019/0000798 Program 4 Healthy Aging in Industrial Environment.
Copyright information: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (