University of Oulu

Rak-Raszewska A. (2019) Experimental Tubulogenesis Induction Model in the Mouse. In: Vainio S. (eds) Kidney Organogenesis. Methods in Molecular Biology, vol 1926. Humana Press, New York, NY.

Experimental tubulogenesis induction model in the mouse

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Author: Rak-Raszewska, Aleksandra1
Organizations: 1University of Oulu, Faculty of Biochemistry and Molecular Medicine, Aapistie 5A, 90220 Oulu
Format: article
Version: accepted version
Access: open
Online Access: PDF Full Text (PDF, 0.2 MB)
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Language: English
Published: Humana Press, 2019
Publish Date: 2021-03-25


Kidney development and induction of tubulogenesis have been studied for almost seven decades. The experimental setup of metanephric mesenchyme induction ex vivo allows to control the environment, to perform cellular manipulations, and to learn about renal development. Since the establishment of the ex vivo kidney culture technique in 1953, the method was modified to suit well the progress in biological and medical fields and still today present many advantages over the traditional in vivo studies.

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Series: Methods in molecular biology
ISSN: 1064-3745
ISSN-E: 1940-6029
ISSN-L: 1064-3745
ISBN: 978-1-4939-9021-4
ISBN Print: 978-1-4939-9020-7
Volume: 1926
Pages: 39 - 51
DOI: 10.1007/978-1-4939-9021-4_4
Host publication: Kidney organogenesis : methods in molecular biology
Host publication editor: Vainio, Seppo
Type of Publication: A3 Book chapter
Field of Science: 1184 Genetics, developmental biology, physiology
Copyright information: © Springer Science+Business Media, LLC, part of Springer Nature 2019. This is a post-peer-review, pre-copyedit version of an article published in Methods in Molecular Biology. The final authenticated version is available online at