University of Oulu

Jyväkorpi, S.K., Ramel, A., Strandberg, T.E. et al. The sarcopenia and physical frailty in older people: multi-component treatment strategies (SPRINTT) project: description and feasibility of a nutrition intervention in community-dwelling older Europeans. Eur Geriatr Med 12, 303–312 (2021).

The sarcopenia and physical frailty in older people: multi-component treatment strategies (SPRINTT) project : description and feasibility of a nutrition intervention in community-dwelling older Europeans

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Author: Jyvakorpi, S. K.1; Ramel, A.2; Strandberg, T. E.1,3;
Organizations: 1Univ Helsinki, Helsinki Univ Cent Hosp, Dept Gen Practice, Tukholmankatu 8 B, Helsinki 00014, Finland.
2Natl Univ Hosp Iceland, Iceland Gerontol Res Ctr, Reykjavik, Iceland.
3Univ Oulu, Ctr Life Course Hlth Res, Oulu, Finland.
4Jagiellonian Univ, Fac Med, Dept Internal Med & Gerontol, Med Coll, Krakow, Poland.
5Jagiellonian Univ, Fac Hlth Sci, Inst Publ Hlth, Dept Nutr & Drug Res,Med Coll, Krakow, Poland.
6Friedrich Alexander Univ Erlangen Ntirnberg, Inst Biomed Aging, Erlangen, Germany.
7Charles Univ Prague, Gen Univ Hosp Prague, Fac Med 1, Dept Gerontol & Geriatr, Nove Mesto, Czech Republic.
8Univ Poitiers Hosp, PRISMATICS Lab Predict Res Spine Neuromodulat Man, Poitiers, France.
9Univ Hosp Limoges, Dept Geriatr, Limoges, France.
10Univ Cattolica Sacro Cuore, Rome, Italy.
11CHU Toulouse, Gerontopole, Toulouse, France.
12Univ Parma, Dept Med & Surg, Parma, Italy.
13Univ Hosp Getafe, Madrid, Spain.
14Univ Hosp Ramon Y Cajal Madrid, Madrid, Spain.
15Med Univ Graz, Graz, Austria.
16Diabet Frail, Med Med Practice, Luton, Beds, England.
17Maastricht Univ, Med Ctr, Maastricht, Netherlands.
18IRCCS INRCA, Ancona, Italy.
19Silesian Hosp, Opava, Czech Republic.
20Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy.
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.6 MB)
Persistent link:
Language: English
Published: John Wiley & Sons, 2021
Publish Date: 2021-04-28


Background: The “Sarcopenia and Physical Frailty in Older People: Multicomponent Treatment Strategies” (SPRINTT) project sponsored a multi-center randomized controlled trial (RCT) with the objective to determine the effect of physical activity and nutrition intervention for prevention of mobility disability in community-dwelling frail older Europeans. We describe here the design and feasibility of the SPRINTT nutrition intervention, including techniques used by nutrition interventionists to identify those at risk of malnutrition and to carry out the nutrition intervention.

Methods: SPRINTT RCT recruited older adults (≥ 70 years) from 11 European countries. Eligible participants (n = 1517) had functional limitations measured with Short Physical Performance Battery (SPPB score 3–9) and low muscle mass as determined by DXA scans, but were able to walk 400 m without assistance within 15 min. Participants were followed up for up to 3 years. The nutrition intervention was carried out mainly by individual nutrition counseling. Nutrition goals included achieving a daily protein intake of 1.0–1.2 g/kg body weight, energy intake of 25–30 kcal/kg of body weight/day, and serum vitamin D concentration ≥ 75 mmol/L. Survey on the method strategies and feasibility of the nutrition intervention was sent to all nutrition interventionists of the 16 SPRINTT study sites.

Results: Nutrition interventionists from all study sites responded to the survey. All responders found that the SPRINTT nutrition intervention was feasible for the target population, and it was well received by the majority. The identification of participants at nutritional risk was accomplished by combining information from interviews, questionnaires, clinical and laboratory data. Although the nutrition intervention was mainly carried out using individual nutritional counselling, other assisting methods were used as appropriate.

Conclusion: The SPRINTT nutrition intervention was feasible and able to adapt flexibly to varying needs of this heterogeneous population. The procedures adopted to identify older adults at risk of malnutrition and to design the appropriate intervention may serve as a model to deliver nutrition intervention for community-dwelling older people with mobility limitations.

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Series: European geriatric medicine
ISSN: 1878-7649
ISSN-E: 1878-7657
ISSN-L: 1878-7649
Volume: 12
Issue: 2
Pages: 303 - 312
DOI: 10.1007/s41999-020-00438-4
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
Funding: Open Access funding provided by University of Helsinki including Helsinki University Central Hospital. The SPRINTT project was funded by Innovative Medicine Initiative (IMI), IMI-JU 115621. SKJ received a grant from Juho Vainio foundation for writing this paper.
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