Hintsala, H.E., Valtonen, R.I.P., Kiviniemi, A. et al. Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease. Sci Rep 11, 2550 (2021). https://doi.org/10.1038/s41598-021-82155-x
Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease
|Author:||Hintsala, Heidi E.1,2,3; Valtonen, Rasmus I. P.1,2; Kiviniemi, Antti4;|
1Center for Environmental and Respiratory Health Research (CERH), University of Oulu, P.O. Box 5000, 90014 Oulu, Finland
2Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland
3Centria University of Applied Sciences, Kokkola, Finland
4Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland
5Department of Internal Medicine, Texas Health Presbyterian Hospital, University of Texas Southwestern Medical Center and the Institute for Exercise and Environmental Medicine, Dallas, USA
6Cardiovascular Research Group, Division of Cardiology, Oulu University Hospital, University of Oulu, Oulu, Finland
7Finnish Defence Forces, Aeromedical Centre, Helsinki, Finland
8Department of Medical Rehabilitation, Oulu University Hospital and Center for Life Course Health Research, University of Oulu, Oulu, Finland
|Online Access:||PDF Full Text (PDF, 1.3 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2021050729180
|Publish Date:|| 2021-05-07
Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state related to exercise in the cold in patients with coronary artery disease (CAD). CAD patients (n = 11) performed moderate-intensity lower-body exercise (walking at 65–70% of HRmax) and rested in neutral (+ 22 °C) and cold (− 15 °C) conditions. In another protocol, CAD patients (n = 15) performed static (five 1.5 min work cycles, 10—30% of maximal voluntary contraction) and dynamic (three 5 min workloads, 56–80% of HRmax) upper-body exercise at the same temperatures. Both datasets consisted of four 30-min exposures administered in random order. Central aortic BP and augmentation index (AI) were noninvasively assessed via pulse wave analyses prior to and 25 min after these interventions. Lower-body dynamic exercise decreased post-exercise central systolic BP (6–10 mmHg, p < 0.001) and AI (1–6%, p < 0.001) both after cold and neutral and conditions. Dynamic upper-body exercise lowered central systolic BP (2–4 mmHg, p < 0.001) after exposure to both temperatures. In contrast, static upper-body exercise increased central systolic BP after exposure to cold (7 ± 6 mmHg, p < 0.001). Acute dynamic lower and upper-body exercise mainly lowers post-exercise central BP in CAD patients irrespective of the environmental temperature. In contrast, central systolic BP was elevated after static exercise in cold. CAD patients likely benefit from year-round dynamic exercise, but hemodynamic responses following static exercise in a cold environment should be examined further.
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3121 General medicine, internal medicine and other clinical medicine
The study was funded through grants from the Finnish Ministry of Education and Culture (TI), Yrjö Jahnsson Foundation (TI, HH) and Juho Vainio Foundation (RV).
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