University of Oulu

Juho-Antti Junno, Lasse Pakanen, Petteri Oura, Unnatural-cause mortality patterns of Northern Finnish men and women diverge in adolescence – A 52-year follow-up, Preventive Medicine Reports, Volume 22, 2021, 101337, ISSN 2211-3355, https://doi.org/10.1016/j.pmedr.2021.101337

Unnatural-cause mortality patterns of Northern Finnish men and women diverge in adolescence : a 52-year follow-up

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Author: Junno, Juho-Antti1,2,3; Pakanen, Lasse4,5; Oura, Petteri6,7,8
Organizations: 1Cancer and Translational Medicine Research Unit, Faculty of Medicine, University of Oulu, Oulu, Finland
2Department of Archaeology, Faculty of Humanities, University of Oulu, Oulu, Finland
3Archaeology, Faculty of Arts, University of Helsinki, Helsinki, Finland
4Forensic Medicine Unit, Finnish Institute for Health and Welfare, Oulu, Finland
5Department of Forensic Medicine, Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu, Oulu, Finland
6Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
7Forensic Medicine Unit, Finnish Institute for Health and Welfare, Helsinki, Finland
8Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 1.1 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2021052030889
Language: English
Published: Elsevier, 2021
Publish Date: 2021-05-20
Description:

Abstract

The Finnish population has a long life expectancy but ranks high in unnatural deaths on the European scale. Mortality has historical regional discrepancy in Finland, as Northern Finns are overrepresented in both natural and unnatural deaths. This study aimed to characterize the age- and sex-related trends in unnatural mortality among Northern Finns. Altogether 12 143 individuals, constituting >95% of births in Northern Finland in 1966, were followed up for a median of 52 years. The mortality patterns of this population were studied using death record data. Crude annual mortality rates were calculated and graphed for 10-year age strata (all-cause, natural-cause, and unnatural-cause mortality, as well as accident, suicide, and homicide mortality). Cox regression was used to analyze the sex discrepancy in mortality. A total of 874 deaths (7.2%) occurred during the follow-up period. Women had 47% and 73% lower risks of any death and unnatural death than men, respectively. From the second decade of life onwards, the unnatural mortality of men was 3–5 times that of women. Accident and suicide mortality rates of men were 2–13 and 2–3 times those of women, respectively. Homicides were rare among either sex. We conclude that Northern Finnish women have a substantially lower risk of all-cause mortality and unnatural mortality than men. To aid the development of preventive strategies, future studies should aim to identify the underlying factors behind unnatural mortality. Primarily, emphasis should be placed on the increased mortality of men from the second decade of life onwards.

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Series: Preventive medicine reports
ISSN: 2211-3355
ISSN-E: 2211-3355
ISSN-L: 2211-3355
Volume: 22
Article number: 101337
DOI: 10.1016/j.pmedr.2021.101337
OADOI: https://oadoi.org/10.1016/j.pmedr.2021.101337
Type of Publication: A1 Journal article – refereed
Field of Science: 3142 Public health care science, environmental and occupational health
319 Forensic science and other medical sciences
Subjects:
Funding: The NFBC1966 study received financial support from University of Oulu, Finland (Grant no. 65354, 24000692), Oulu University Hospital, Finland (Grant no. 2/97, 8/97, 24301140), Ministry of Health and Social Affairs, Finland (Grant no. 23/251/97, 160/97, 190/97), National Institute for Health and Welfare, Helsinki, Finland (Grant no. 54121), Regional Institute of Occupational Health, Oulu, Finland (Grant no. 50621, 54231) and European Regional Development Fund ERDF (Grant no. 539/2010 A31592).
Copyright information: © 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  https://creativecommons.org/licenses/by/4.0/