Ruixue Zhu, Tatiana Avsievich, Alexey Popov, Alexander Bykov, and Igor Meglinski "In vitro influence of 520 nm diode laser irradiation on red blood cell spontaneous aggregation studied by optical tweezers and light microscopy", Proc. SPIE 11798, Optical Trapping and Optical Micromanipulation XVIII, 1179809 (1 August 2021); https://doi.org/10.1117/12.2595118
In vitro influence of 520 nm diode laser irradiation on red blood cell spontaneous aggregation studied by optical tweezers and light microscopy
|Author:||Zhu, Ruixue1; Avsievich, Tatiana1; Popov, Alexey2;|
1Optoelectronics and Measurement Techniques Laboratory, University of Oulu, 90570 Oulu, Finland
2VTT Technical Research Centre of Finland, Kaitoväylä 1, 90590, Oulu, Finland
3College of Engineering and Physical Sciences, Aston University, Birmingham, B4 7ET, UK
|Online Access:||PDF Full Text (PDF, 4.1 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2021092747160
|Publish Date:|| 2021-09-27
The laser has biomodulation effects on blood properties thus could regulate the microcirculation. The laser-RBC interaction mechanism is unclear, whereas most studies provide statistical results and lack detailed observations of laser irradiation effects on blood rheology. This study is designated to probe the in vitro effects of 520 nm diode laser irradiation on red blood cells (RBCs) mutual interaction properties in spontaneous aggregation process in autologous plasma by optical tweezers (OTs), with an attempt to reveal the laser-RBC interaction outcomes at a single-cell level. The results preliminarily show that though the laser irradiation statistically inhibited the increase of the size of RBC aggregates compared with the non-irradiating group, the aggregation force between single RBCs increased slightly with the time of irradiation.
Proceedings of SPIE
|Pages:||1 - 7|
Optical Trapping and Optical Micromanipulation XVIII, 1–5 August 2021. San Diego, USA
|Host publication editor:||
Spalding, Gabriel C.
Optical Trapping and Optical Micromanipulation
|Type of Publication:||
A4 Article in conference proceedings
|Field of Science:||
222 Other engineering and technologies
This work was partially funded by the China Scholarship Council (CSC No.201706410089, R.Z.). R.Z. acknowledges X.Y. Su (School of Science, Beijing Jiaotong University, Beijing, China) for technical help in laser irradiation source selection. The authors also acknowledge the contribution of Russian Science Foundation (Projects: 19-72-30012 and 20-64-46003). I.M. acknowledges partial support from the Academy of Finland (project 325,097).
|Academy of Finland Grant Number:||
325097 (Academy of Finland Funding decision)
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