University of Oulu

Miia Länsitie, Maarit Kangas, Jari Jokelainen, Mika Venojärvi, Eeva Vaaramo, Pirjo Härkönen, Sirkka Keinänen-Kiukaanniemi, Raija Korpelainen, Association between accelerometer-measured physical activity, glucose metabolism, and waist circumference in older adults, Diabetes Research and Clinical Practice, Volume 178, 2021, 108937, ISSN 0168-8227, https://doi.org/10.1016/j.diabres.2021.108937

Association between accelerometer-measured physical activity, glucose metabolism, and waist circumference in older adults

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Author: Länsitie, Miia1,2,3; Kangas, Maarit3; Jokelainen, Jari4,5;
Organizations: 1Department of Sports and Exercise Medicine, Oulu Deaconess Institute Foundation sr., Oulu, Finland
2Center for Life Course Health Research, University of Oulu, Oulu, Finland
3Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland
4Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Finland
5Unit of General Practice, Oulu University Hospital, Oulu, Finland
6Institute of Biomedicine, Sports and Exercise Medicine, University of Eastern Finland, Kuopio, Finland
7Healthcare and Social Services of Selänne, Pyhäjärvi, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.5 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2021101250677
Language: English
Published: Elsevier, 2021
Publish Date: 2021-10-12
Description:

Abstract

Aims: To examine the association of physical activity (PA) and sedentary time (ST) with glucose metabolism according to waist circumference (WC) in older people.

Methods: A population-based sample of 702 individuals (aged 67–70 years) wore wrist-worn accelerometers for two weeks and underwent an oral glucose tolerance test. The associations between moderate-to-vigorous (MVPA) and light (LPA) PA, ST, and glucose metabolism across the tertiles of WC were analysed using general linear regression.

Results: Among highest WC tertile, LPA negatively associated with fasting insulin (β = − 0.047, 95% CI − 0.082 to − 0.012), HOMA-IR (β = − 0.098, 95% CI − 0.184 to − 0.012), and HOMA-β (β = − 3.367, CI − 6.570 to − 0.783). ST associated with 120 min glucose (β = 0.140, CI 0.021 to 0.260). Among lowest WC tertile, MVPA negatively associated with 30 min insulin (β = − 0.086, 95% CI − 0.168 to − 0.004) and 120 min insulin (β = − 0.160, 95% CI − 0.257 to − 0.063) and positively associated with Matsuda index (β = 0.076, 95% CI 0.014 to 0.139). Light PA negatively associated with 120 min insulin (β = − 0.054, 95% CI − 0.104 to − 0.005).

Conclusion: With the limitation of the cross-sectional study, reducing ST and increasing LPA may be beneficial for glucose metabolism among abdominally obese older adults. Lean older adults could benefit more from increasing MVPA.

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Series: Diabetes research and clinical practice
ISSN: 0168-8227
ISSN-E: 1872-8227
ISSN-L: 0168-8227
Volume: 178
Article number: 108937
DOI: 10.1016/j.diabres.2021.108937
OADOI: https://oadoi.org/10.1016/j.diabres.2021.108937
Type of Publication: A1 Journal article – refereed
Field of Science: 3121 General medicine, internal medicine and other clinical medicine
315 Sport and fitness sciences
Subjects:
Funding: This study was supported by the City of Oulu, Finland; Ministry of Education, Finland; the University of Oulu, Finland; the Deaconess Institute Foundation sr., Oulu, Finland; the University Hospital of Oulu, Finland; and the Päivikki and Sakari Sohlberg Foundation, Finland.
Copyright information: © 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  https://creativecommons.org/licenses/by/4.0/