Vaičiulis, V., Jaakkola, J.J.K., Radišauskas, R. et al. Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015. Sci Rep 11, 17062 (2021). https://doi.org/10.1038/s41598-021-96366-9
Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
|Author:||Vaičiulis, Vidmantas1,2; Jaakkola, Jouni J. K.3,4,5,6; Radišauskas, Ričardas1,7;|
1Department of Environmental and Occupational Medicine, Lithuanian University of Health Sciences, Tilzes St. 18, 47181, Kaunas, Lithuania
2Health Research Institute, Lithuanian University of Health Sciences, Tilzes St. 18, 47181, Kaunas, Lithuania
3Faculty of Medicine, Center for Environmental and Respiratory Health Research (CERH), University of Oulu, Oulu, Finland
4Biocenter Oulu, University of Oulu, Oulu, Finland
5Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland
6Finnish Meteorological Institute, Helsinki, Finland
7Laboratory of Population Studies, Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu St. 15, 50103, Kaunas, Lithuania
8Department of Preventive Medicine, Lithuanian University of Health Sciences, Tilzes St. 18, 47181, Kaunas, Lithuania
|Online Access:||PDF Full Text (PDF, 0.9 MB)|
|Persistent link:|| http://urn.fi/urn:nbn:fi-fe2021101250715
|Publish Date:|| 2021-10-12
Acute myocardial infarction (AMI) is a major public health problem. Cold winter weather increases the risk of AMI, but factors influencing susceptibility are poorly known. We conducted an individual-level case-crossover study of the associations between winter cold spells and the risk of AMI, with special focus on survival at 28 days and effect modification by age and sex. All 16,071 adult cases of AMI among the residents of the city of Kaunas in Lithuania in 2000–2015 were included in the study. Cold weather was statistically defined using the 5th percentile of frequency distribution of daily mean temperatures over the winter months. According to conditional logistic regression controlling for time-varying and time-invariant confounders, each additional cold spell day during the week preceding AMI increased the risk of AMI by 5% (95% CI 1–9%). For nonfatal and fatal cases, the risk increase per each additional cold spell day was 5% (95% CI 1–9%) and 6% (95% CI − 2–13%), respectively. The effect estimate was greater for men (OR 1.07, 95% CI 1.02–1.12) than for women (OR 1.02, 95% CI 0.97–1.08), but there was no evidence of effect modification by age. Evidence on factors increasing susceptibility is critical for targeted cold weather planning.
|Type of Publication:||
A1 Journal article – refereed
|Field of Science:||
3142 Public health care science, environmental and occupational health
This project has received funding from the European Social Fund (Title: “The impact of climate change on public health”, Project No. 09.3.3-LMT-K-712-19-0002) under Grant Agreement with the Research Council of Lithuania (LMTLT). J.J. and N.R. were supported by the Academy of Finland [Grant Number 310372 (GLORIA Consortium)].
|Academy of Finland Grant Number:||
310372 (Academy of Finland Funding decision)
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