University of Oulu

Ville-Veikko Telkki, Mateusz Urbańczyk, Vladimir Zhivonitko, Ultrafast methods for relaxation and diffusion, Progress in Nuclear Magnetic Resonance Spectroscopy, Volumes 126–127, 2021, Pages 101-120, ISSN 0079-6565,

Ultrafast methods for relaxation and diffusion

Saved in:
Author: Telkki, Ville-Veikko1; Urbańczyk, Mateusz1,2; Zhivonitko, Vladimir1
Organizations: 1NMR Research Unit, University of Oulu, P.O. Box 3000, FIN-90014, Finland
2Centre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 3.4 MB)
Persistent link:
Language: English
Published: Elsevier, 2021
Publish Date: 2021-11-15


Relaxation and diffusion NMR measurements offer an approach to studying rotational and translational motion of molecules non-invasively, and they also provide chemical resolution complementary to NMR spectra. Multidimensional experiments enable the correlation of relaxation and diffusion parameters as well as the observation of molecular exchange phenomena through relaxation or diffusion contrast. This review describes how to accelerate multidimensional relaxation and diffusion measurements significantly through spatial encoding. This so-called ultrafast Laplace NMR approach shortens the experiment time to a fraction and makes even single-scan experiments possible. Single-scan experiments, in turn, significantly facilitate the use of nuclear spin hyperpolarization methods to boost sensitivity. The ultrafast Laplace NMR method is also applicable with low-field, mobile NMR instruments, and it can be exploited in many disciplines. For example, it has been used in studies of the dynamics of fluids in porous materials, identification of intra- and extracellular metabolites in cancer cells, and elucidation of aggregation phenomena in atmospheric surfactant solutions.

see all

Series: Progress in nuclear magnetic resonance spectroscopy
ISSN: 0079-6565
ISSN-E: 1873-3301
ISSN-L: 0079-6565
Volume: 126-127
Pages: 101 - 120
DOI: 10.1016/j.pnmrs.2021.07.001
Type of Publication: A2 Review article in a scientific journal
Field of Science: 114 Physical sciences
116 Chemical sciences
Funding: The authors acknowledge the financial support of the European Research Council (ERC) under Horizon 2020 (H2020/2018-2022/ERC grant agreement no. 772110), Academy of Finland (grants #289649, 294027, 319216 and 323480), the CA15209 COST Action (EURELAX) and Kvantum Institute (University of Oulu).
EU Grant Number: (772110) UFLNMR - Ultrafast Laplace NMR
Academy of Finland Grant Number: 289649
Detailed Information: 289649 (Academy of Finland Funding decision)
294027 (Academy of Finland Funding decision)
319216 (Academy of Finland Funding decision)
323480 (Academy of Finland Funding decision)
Copyright information: © 2021 The Authors. Published by Elsevier B.V.This is an open access article under the CC BY license (