University of Oulu

Pakkanen, P., Ilmarinen, T., Halme, E. et al. T1 glottic laryngeal cancer: the role of routine follow-up visits in detecting local recurrence. Eur Arch Otorhinolaryngol 278, 4863–4869 (2021). https://doi.org/10.1007/s00405-021-06983-3

T1 glottic laryngeal cancer : the role of routine follow-up visits in detecting local recurrence

Saved in:
Author: Pakkanen, Pihla1; Ilmarinen, Taru1; Halme, Elina2;
Organizations: 1Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, P.O. Box 263, 00029, Helsinki, Finland
2Department of Otorhinolaryngology-Head and Neck Surgery, University of Tampere and Tampere University Hospital, Tampere, Finland
3Department of Otorhinolaryngology-Head and Neck Surgery, University of Turku and Turku University Hospital, Turku, Finland
4Department of Otorhinolaryngology-Head and Neck Surgery, University of Oulu and Oulu University Hospital, Oulu, Finland
5Department of Otorhinolaryngology-Head and Neck Surgery, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland
6Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
7Department of Oral Pathology and Radiology, University of Turku, Turku, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.7 MB)
Persistent link: http://urn.fi/urn:nbn:fi-fe2021112557088
Language: English
Published: Springer Nature, 2021
Publish Date: 2021-11-25
Description:

Abstract

Purpose: We assessed the treatment outcome and the benefits of routine follow-up visits in T1 glottic laryngeal squamous cell carcinoma (LSCC).

Methods: Medical records of patients diagnosed with stage T1 glottic LSCC (N = 303) in five Finnish university hospitals between 2003 and 2015 were reviewed. Moreover, data from the Finnish Cancer Registry and the Population Register Center were collected.

Results: Of all 38 recurrences, 26 (68%) were detected during a routine follow-up visit, and over half (21 of 38, 55%) presented without new symptoms. Primary treatment method (surgery vs. radiotherapy) was not connected with 5-year disease-specific survival (DSS) or laryngeal preservation rate.

Conclusion: The majority of recurrences were detected on a routine follow-up visit, and local recurrences often presented without new symptoms. Routine post-treatment follow-up of T1 glottic LSCC seems beneficial.

Trial registration: Trial registration number and date of registration HUS/356/2017 11.12.2017.

see all

Series: European archives of oto-rhino-laryngology
ISSN: 0937-4477
ISSN-E: 1434-4726
ISSN-L: 0937-4477
Volume: 278
Issue: 12
Pages: 4863 - 4869
DOI: 10.1007/s00405-021-06983-3
OADOI: https://oadoi.org/10.1007/s00405-021-06983-3
Type of Publication: A1 Journal article – refereed
Field of Science: 3125 Otorhinolaryngology, ophthalmology
3122 Cancers
Subjects:
Funding: Open access funding provided by University of Helsinki including Helsinki University Central Hospital. The study was funded by Helsinki University Hospital research funds.
Copyright information: © The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
  https://creativecommons.org/licenses/by/4.0/