University of Oulu

Junttola, U, Lahtinen, S, Liisanantti, J, Vakkala, M, Kaakinen, T, Isokangas, J-M. Medical complications and outcome after endovascular therapy for acute ischemic stroke. Acta Neurol Scand. 2021; 144: 623– 631.

Medical complications and outcome after endovascular therapy for acute ischemic stroke

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Author: Junttola, Ulla1,2; Lahtinen, Sanna1,3; Liisanantti, Janne1,3;
Organizations: 1Research Group of Surgery, Anesthesiology and Intensive Care, Medical Research Center Oulu, Oulu, Finland
2Departments of Neurology, Oulu University Hospital, Oulu, Finland
3Deparment of Anesthesiology, Oulu University Hospital, Oulu, Finland
4Department of Radiology, Oulu University Hospital, Oulu, Finland
Format: article
Version: published version
Access: open
Online Access: PDF Full Text (PDF, 0.5 MB)
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Language: English
Published: John Wiley & Sons, 2021
Publish Date: 2021-12-03


Aim: Endovascular therapy (EVT) in acute stroke is an effective but invasive treatment which is frequently followed by various complications. The aim of the present study was to examine the rate of medical complications and other adverse events following EVT.

Methods: Retrospective single-center study of 380 consecutive stroke patients who received EVT between the years 2015–2019.

Results: A total of 234 (61.6%) patients had at least one recorded medical complication. The most common complication was pneumonia in 154 (40.5%) patients, followed by acute cardiac insufficiency in 134 (35.3%), and myocardial infarction in 22 (5.8%) patients. In multivariate analysis, the need for general anesthesia (OR 3.8 (1.9–7.7)), Charlson Comorbidity Index >3 (OR 1.3 (1.1–1.5)), male gender (1.9 (1.1–1.3)) and high National Institutes of Health Stroke Scale (NIHSS) score at admission (1.1 (1.0–1.2)) were associated with medical complications.

Conclusion: Medical complications are common among unselected stroke patients undergoing EVT. Both comorbidity and stroke severity have an influence on medical complications. Early recognition of complications is essential, because vast majority of patients encountering medical complications have a poor short-term outcome.

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Series: Acta neurologica scandinavica
ISSN: 0001-6314
ISSN-E: 1600-0404
ISSN-L: 0001-6314
Volume: 144
Issue: 6
Pages: 623 - 631
DOI: 10.1111/ane.13501
Type of Publication: A1 Journal article – refereed
Field of Science: 3124 Neurology and psychiatry
3126 Surgery, anesthesiology, intensive care, radiology
Copyright information: © 2021 The Authors. Acta Neurologica Scandinavica published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.